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Regulation of intraocular pressure and pupil size by beta-blockers and epinephrine


, : Regulation of intraocular pressure and pupil size by beta-blockers and epinephrine. Archives of Ophthalmology 98(12): 2182-2184

The interaction of adrenergic beta-receptor blockers and epinephrine on intraocular pressure and pupil size was investigated in healthy volunteers. Oral (atenolol and propranolol) and local (timolol) beta-blockers were studied. The experiment was carried out under double-blind randomized crossover conditions. The results showed that the combination of oral beta-blockers with topical epinephrine had an additive hypotensive effect on IOP, while timolol and epinephrine eyedrops both reduced the IOP used alone, but combined had an antagonistic effect, resulting in the disappearance of the epinephrine-mediated IOP reduction.

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Accession: 044174659

PMID: 6108756

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Christensen, M.; Fennell, D. I.; Backus, M. P., 1964: Aspergillus kanagawaensis and related species in Wisconsin forest soils. Recognition of a new major group in the Aspergilli, the Aspergillus cervinus group, is proposed and a key to the known spp. provided. The new group brings together 4 taxa: A. cervinus Massee, A. kanagawaensis Nehira, A. mutans McLennan et Ducker,...

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