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Residues defining V beta specificity in staphylococcal enterotoxins

Residues defining V beta specificity in staphylococcal enterotoxins

Nature Structural Biology 2(8): 680-686

The three-dimensional structure of staphylococcal enterotoxin C2 has been determined at 2.7 A resolution by x-ray diffraction, while the structures of enterotoxins A and E have been modelled based on their sequence homology to other staphylococcal enterotoxins. The T-cell receptor-binding sites of staphylococcal enterotoxin (SE) B and SEC2 are compared and the stereochemical interactions likely to be responsible for their differing V beta specificities are identified. A similar comparison is made between SEA and SEE.

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Accession: 044212829

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PMID: 7552730

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