Serum haptoglobin and alpha 1-acid glycoprotein as indicators of the effectiveness of cis-diamminedichloroplatinum (CDDP) in ovarian cancer patients--a preliminary report

Fish, R.G.; Gill, T.S.; Adams, M.; Kerby, I.

European Journal of Cancer and Clinical Oncology 20(5): 625-630

1984


ISSN/ISBN: 0277-5379
PMID: 6539699
Accession: 044306920

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Abstract
Twenty-one patients with adenocarcinoma of the ovary were given a maximum of five courses of CDDP by i.v. infusion every 4 weeks. With one exception, the serum levels of both haptoglobin and alpha 1-acid glycoprotein correlate with tumour burden before therapy and at follow-up. It is suggested that a more accurate assessment of the effectiveness of CDDP therapy may be obtained by estimating these serum proteins before each infusion than by an abdominal examination.