EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
EurekaMag PDF Full Text Supply ServicePDF Full Text Supply Service
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn
Follow on LinkedInFollow on Tumblr

+ Translate

Specificity patterns of different types of human fucosidase. Recognition of a certain region of the pyranose ring in sugars by the enzymes


, : Specificity patterns of different types of human fucosidase. Recognition of a certain region of the pyranose ring in sugars by the enzymes. Biochimica et Biophysica Acta 659(2): 434-444

Data on the hydrolysis of fucosides, galactosides and arabinosides by different types of fucosidase are presented. The comparative study of the splitting of alpha-L-fucoside and beta-D-arabinoside with a similar structure at C1--C4 of the pyranose ring and the preparation of the enzyme by affinity chromatography showed that both substrates were hydrolysed by the same enzyme, alpha-L-fucoside(beta-D-arabinoside)hydrolase. The analogous investigation of the hydrolysis of beta-D-fucoside, beta-D-galactoside and alpha-L-arabinoside with a similar structure at C1--C4 of the pyranose ring demonstrated that these glycosides were split by the same enzyne, beta-D-fucoside(beta-D-galactoside, alpha-L-arabinoside)hydrolase, the activity of which is decreased dramatically in GM1-gangliosidosis. The data obtained support the assumption that the specific action of different types of fucosidase is due to recognition by these enzymes of C1--C4 of the pyranose ring in the corresponding substrates. The problems of differential diagnosis of some glycosidoses (focosidosis, GM1-gangliosidosis and Fabry disease) are discussed on the basis of the data obtained.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 044374910

PMID: 6789883

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Gerath Robert F., 2007: Landslide hazard assessments and public policy in British Columbia. 'Guidelines for Legislated Landslide Assessments for Proposed Residential Development in British Columbia' was published by the Association of Professional Engineers and Geoscientists of BC (APEGBC) in 2006. The document notes several an...

Zhang, K.; Yuan, Z.; Bing, Y.; Chen, X.; Ding, X.; Chen, D., 2008: Effects of active immunization against cholecystokinin 8 on performance, contents of serum hormones, and expressions of CCK gene and CCK receptor gene in pigs. This study was conducted to investigate the effects of active immunization against cholecystokinin 8 (CCK(8)) on the content of serum CCK, expression of CCK, and CCK receptor gene in pigs. The subjects for this experiment were 15 pigs divided into...

Beck J.R., 1974: An overview of american society for testing and materials activities in establishing standards for vertebrate pest control materials. Proceedings Of The Vertebrate Pest Conference: 62

Pistelli, L.; Noccioli, C.; Martera, M.; Giamperi, L.; Bucchini, A.; Fraternale, D.; Ricci, D., 2006: Antioxidant flavonol glycosides from Dorycnium hirsutum. Seven flavonol glycosides were isolated and identified from the aerial parts of Dorycnium hirsutum, together with catechin, D-pinitol, beta -sitosterol, and stearic acid. The extracts and the isolated flavonol glycosides were evaluated for their...

Piedade, Sérgio.Rocha.; Dal Fabbro, Iácio.Maria.; Mischan, M.Maria., 2006: Cyclic-loading of the human gracilis and semitendinosus muscle tendons: study of young adult cadavers. During knee ligament reconstruction, the tendon graft is tensioned to prevent the occurrence of excessive graft elongation during the postoperative period. Tensioning may be achieved by applying a cyclic or static load to the graft during fixation...

Wagner H.; Munster R., 1967: The structure of silybin a new flavananol substance from the fruits of silybum marianum d abstract. Lloydia (Cincinnati) 30(3): 287

Moon, Virgil H., 1946: Parenchymatous degeneration related to anoxia. Amer Jour Path 22(3): 656-658

Pal, R. N.; Singh, R.; Vij, V. K.; Sharma, J. N., 1976: Effect of gibberellins GA3, GA4+7 and GA13 on seed germination and subsequent seedling growth in Early Muscat grape (Vitis vinifera). After-ripened seeds were treated with 0, 50, 100, 250, 500 or 1000 p.p.m. of each gibberellin. All gibberellins (except GA4+7) at concentrations beyond 50 p.p.m. promoted germination, especially lower concentrations. GA4+7 at 1000 p.p.m. inhibited...

Dailey, P. J.; Graves, R. C., 1976: Gross internal anatomy of the madagascar hissing cockroach gromphadorhina portentosa. The gross internal anatomy of the digestive, circulatory, nervous and reproductive systems of the Madagascar hissing cockroach, G. portentosa (Schaum), are described and illustrated.

Sun, Chengyong; Feoli, Enrico; Lagonegro, Mario, 1992: Measuring climatic niche width and overlap of vegetation types of China. Two approaches for niche width and overlap are compared based on vegetation types and climatic data from China. One approach applies the trajectory concept and uses a dynamic space, the other applies the hypervolume concept and uses both dynamic a...