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Specimen handling and high-performance liquid chromatographic determination of furosemide


, : Specimen handling and high-performance liquid chromatographic determination of furosemide. Journal of Chromatography 229(1): 129-139

A simple high-performance liquid chromatographic method to measure furosemide in plasma and urine is described. Furosemide fluoresces best, but is unstable, at acidic pH and is subject to photochemical degradation. These factors were analysed and the results prompted changes in previously described methods. All specimens were very carefully protected from light; extraction and acidification were done with acetic acid instead of hydrochloric acid. With these precautions no 4-chloro-5-sulphamoylanthranilic acid was found in biological specimens. The main metabolite was furosemide glucuronide (20% of furosemide excretion). Sensitivity was 0.1 and 0.5 microgram/ml for plasma and urine, respectively. The applicability of our method for furosemide studies is demonstrated.

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Accession: 044374971

PMID: 7085820

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Matsumura, S. O.; Trpeski, L.; Pong Porter, S.; Comette, M.; Network, Canadian Bacterial Surveillance; De Azavedo, J. C.; Mcgeer, A.; Low, D. E., 1997: Cross Canada surveillance of drug-resistant Streptococcus pneumoniae from 1988 to 1996. Abstracts of the Interscience Conference on Antimicrobial Agents & Chemotherapy 37: 134

STEWARD, R.L.; WADE, H., 1956: Henry Wade. Journal of Pathology and Bacteriology 71(2): 550-553

Murphy, C. I.; Young, E., 1996: Baculovirus vectors for expression of secretory and membrane-bound proteins. Official Gazette of the United States Patent & Trademark Office Patents 1186(2): 1174, May 14

Stucky Richard K.; Krishtalka Leonard, 1991: This application of geologic remote sensing to vertebrate biostratigraphy; general results from the Wind River basin, Wyoming. The Mountain Geologist 28(2-3): 75-82

Raun, V. T., 1985: Proposed law on cooperative banking. The proposed law will enable cooperative banks in Denmark to act as independent financial institutions. The article discusses the new rules and members' rights and obligations.

Corbi, N.; Di Padova, M.; De Angelis, R.; Bruno, T.; Libri, V.; Iezzi, S.; Floridi, A.; Fanciulli, M.; Passananti, C., 2002: The alpha-like RNA polymerase II core subunit 3 (RPB3) is involved in tissue-specific transcription and muscle differentiation via interaction with the myogenic factor myogenin. RNA polymerase II core subunit 3 (RPB3) is an a-like core subunit of RNA polymerase II (pol II). It is selectively down-regulated upon treatment with doxorubicin (dox). Due to the failure of skeletal muscle cells to differentiate when exposed to d...

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Gnauck, K.; Carlson, D.; Barry, R.; Haire Joshu, D.; Miller, P.; Jaffe, D., 1996: Systems issues in pediatric emergency care The perspective of the primary care physician. Journal of Investigative Medicine 44(7): 403A

Vathi, Kico; Fili, Ilia; Odin, Gilles Serge, 1994: Volcanoclastic layers of the Lower and Middle Miocene in Albania. Giornale di Geologia (Bologna) 56(1): 115-123