+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Standardized antimicrobial disc susceptibility testing of anaerobic bacteria: in vitro susceptibility of Clostridium perfringens to nine antibiotics



Standardized antimicrobial disc susceptibility testing of anaerobic bacteria: in vitro susceptibility of Clostridium perfringens to nine antibiotics



Antimicrobial Agents and ChemoTherapy 2(4): 320-325



The in vitro susceptibility of 43 strains of Clostridium perfringens to nine antibiotics was determined by a standardized test for rapid-growing anaerobes. Good correlation was established between the agar dilution susceptibility and the disc diffusion susceptibility results. The inhibition zone diameters around the antibiotic discs, however, were generally much smaller than those of gram-negative anaerobes previously studied. All of the strains tested were susceptible in vitro to chloramphenicol, clindamycin, doxycycline, minocycline, penicillin, and vancomycin. Erythromycin showed poor in vitro activity against this organism, with only 7% of the strains susceptible, 72% intermediate in susceptibility, and 21% resistant. In tests of the 43 strains against lincomycin, 58% were susceptible, 32.5% were intermediate in susceptibility, and 9.5% were resistant. Against tetracycline, 37% of the strains were intermediate in susceptibility and the rest were susceptible.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 044390512

Download citation: RISBibTeXText

PMID: 4363787

DOI: 10.1128/aac.2.4.320


Related references

Standardized antimicrobial disc susceptibility testing of anaerobic bacteria. I. Susceptibility of Bacteroides fragilis to tetracycline. Applied Microbiology 23(2): 268-275, 1972

Susceptibility of anaerobic bacteria to nine antimicrobial agents and demonstration of decreased susceptibility of Clostridium perfringens to penicillin. Antimicrobial Agents and ChemoTherapy 19(1): 51-55, 1981

Susceptibility of Bacteroides fragilis to six antibiotics determined by standardized antimicrobial disc susceptibility testing. Antimicrobial Agents and ChemoTherapy 3(2): 188-193, 1973

Comparison of agar dilution and broth microdilution methods of anaerobic antimicrobial susceptibility testing using several veterinary antibiotics against Clostridium perfringens strains originating from porcine and avian sources. Anaerobe 5(5): 561-569, 1999

Standardized single-disc method for antibiotic susceptibility testing of anaerobic bacteria. Antimicrobial Agents and ChemoTherapy 1(6): 451-459, 1972

Susceptibility of anaerobic bacteria to 9 anti microbial agents and demonstration of decreased susceptibility of clostridium perfringens to penicillin. Antimicrobial Agents & Chemotherapy 19(1): 51-55, 1981

Antibiotic susceptibility testing of anaerobic bacteria by the standardized disc diffusion method with special reference to bacteroides fragilis. Scandinavian Journal of Infectious Diseases 7(1): 59-66, 1975

Susceptibility of anaerobic bacteria to metronidazole, ornidazole, and tinidazole and routine susceptibility testing by standardized methods. Antimicrobial Agents and ChemoTherapy 11(4): 631-637, 1977

First Argentine consensus guidelines for in vitro antimicrobial susceptibility testing of clinically relevant anaerobic bacteria in humans/ Anaerobic Subcommittee of the Asociación Argentina de Microbiología. Revista Argentina de Microbiologia 43(1): 51-66, 2011

In vitro susceptibility of clostridium perfringens to 6 antibiotics. Abstracts of the Annual Meeting of the American Society for Microbiology 72: 95, 1972

Antimicrobial susceptibility testing of bacteria isolated from animals: methods for in-vitro susceptibility testing and their suitability with regard to the generation of the most useful data for therapeutic applications. Berliner und Munchener Tierarztliche Wochenschrift 116(9-10): 353-361, 2003

Antimicrobial susceptibility testing of bacteria isolated from animals: methods for in-vitro susceptibility testing and their suitability with regard to the generation of most useful data for therapeutic applications. Berliner und Munchener Tierarztliche Wochenschrift 116(9/10): 353-361, 2003

In vitro susceptibility of Clostridium perfringens to 6 antimicrobial agents. Revista Medica de Chile 110(11): 1110-1112, 1982

The Susceptibility of Clostridium perfringens Type A to Cephalosporin C Antibiotics in vitro. Chemotherapy 16(1): 11-17, 1971

The susceptibility of Clostridium perfringens type A to cephalosporin C antibiotics in vitro. ChemoTherapy 16(1): 11-17, 1971