EurekaMag.com logo
+ Site Statistics
References:
48,253,228
Abstracts:
22,798,842
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

The prevalence and significance of elevated dehydroepiandrosterone sulfate levels in anovulatory women


, : The prevalence and significance of elevated dehydroepiandrosterone sulfate levels in anovulatory women. Fertility and Sterility 42(1): 76-81

One hundred nineteen euprolactinemic anovulatory infertility patients who were being evaluated for induction of ovulation with clomiphene citrate were studied to determine the prevalence of increased adrenal androgen (AA) secretion in this group. Fifty percent of these patients exhibited increased AA secretion, as evidenced by an elevated serum dehydroepiandrosterone sulfate (DHEA-S) level. Seventy-seven percent of these women with elevated levels of DHEA-S were nonhirsute . Twenty-six patients with elevated serum DHEA-S levels underwent adrenocorticotropic hormone (ACTH) stimulation tests in order to determine a possible mechanism(s) for the increase in DHEA-S. Plasma ACTH, as well as total, low-density lipoprotein, and high-density lipoprotein cholesterol were also measured. These levels were normal and did not correlate with the elevated levels of DHEA-S. Seven of 16 patients (34%) had exaggerated responses of serum DHEA-S and of 17-OH pregnenolone to ACTH stimulation. In six of these seven patients, our data suggested the occurrence of a mild deficiency of 3 beta-ol dehydrogenase-isomerase. All of these six patients were considered to have polycystic ovary syndrome. While these data do not explain the increased AA secretion in the majority of patients with elevated levels of DHEA-S, we suggest that serum DHEA-S is frequently elevated in anovulatory infertile patients.

(PDF 0-2 workdays service)

Order PDF Full Text

Close
Close

Click here to order any other PDF Full Text


Accession: 044714537

PMID: 6327404

PDF Full Text: Submit


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Other references

Ozerdem, U.; Wells, J.; Hoda, S.A., 2015: Hyaline globules in mammary myofibroblastoma: a case report. A 52-year-old otherwise healthy woman presented with a solitary firm mass in the right breast. Histopathological evaluation of the 1.5-cm mass showed a mammary myofibroblastoma of the conventional spindle-cell type. High-power examination of hemat...

Munoz B.; Bolander F.F.Jr, 1989: Prolactin regulation of mouse mammary tumor virus mmtv expression in normal mouse mammary epithelium. The hormonal regulation of mouse mammary tumor virus (MMTV) RNA in normal mouse mammary epithelium was studied in an explant system. In tissue from parous mice physiological concentrations of prolactin stimulated MMTV expression, while only pharma...

Peterson, L. M.; Jeffery, N. M.; Thies, F.; Sanderson, P.; Newsholme, E. A.; Calder, P. C., 1997: N-3 polyunsaturated fatty acids have differential effects on lymphocyte functions and cell-mediated immunity in the rat. Immunology 92(SUPPL 1): 92, Dec

ROKA, L.; KONIG, G.; RUBNER, H., 1958: Fermentative oxidation of rho-hydroxyphenylpyruvic acid to homogentisic acid. Hoppe-Seyler's Zeitschrift für Physiologische Chemie 313(): 87-96

ABELSON, N.M., 1949: Preventable factors in erythroblastosis fetalis. Philadelphia Medicine 44(32): 1227-1231

Mirra, V., 1982: Use of functional casts in leg fractures. La Chirurgia Degli Organi di Movimento 68(3): 405-411

Walsh Timothy J.; Logan Robert L.; Neal Kenneth G., 1997: The Canyon River Fault, an active fault in the southern Olympic Range, Washington. Washington Geology 25(4): 21-24

Shanahan, J., 1944: Glossy Ibis inCo. Wexford. Irish Naturalists' Journal, 8: 178-179

Crosnier, A., 1987: Les especes indo-ouest-pacifiques d'eau profonde du genre Metapenaeopsis (Crustacea Decapoda Penaeidae). Bulletin du Museum National d'Histoire Naturelle Section A Zoologie Biologie et Ecologie Animales, 92: 409-453

Purnachandra Rao, V.; Purnachander Reddy, N.; Madhusudana Rao, Ch., 1988: Clay mineral distribution in the shelf sediments off the northern part of the east coast of India. Forty-eight sediment samples from the continental shelf between Visakhapatnam and the Ganges were analysed by X-ray diffraction for the composition and distribution of clay minerals. Estuarine samples of the Hooghly are dominated by illite and chl...