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A kinder, gentler ddC... for $7,200 a year



A kinder, gentler ddC... for $7,200 a year



GMHC Treatment Issues 9(12): 2-2



Hoffman-LaRoche's saquinavir (Invirase) is the first protease inhibitor to be granted approval by the Food and Drug Administration (FDA). The drug can be marketed for use in people with advanced HIV disease in combination with approved nucleoside analogs, such as AZT and ddC. Invirase has relatively minor side effects. The improvement in CD4 counts is small and short-lived, and it performs no better alone than does ddC. Saquinavir's main advantage is the relatively benign way it has of boosting the mediocre performance of nucleoside analogs. Its primary disadvantage is the retail price of $7,200 per year.

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Accession: 045066436

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PMID: 11362996


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