+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A new biological irradiator for the laboratory



A new biological irradiator for the laboratory



La Radiologia Medica 86(1-2): 127-134



The use of high doses (15-20 Gy) of X- or gamma-rays to irradiate blood-derived materials is a common practice by now. It is usual especially when materials must be transfused into non-immunocompetent patients. This is done to avoid the so-called GVH disease. Nowadays, for this purpose, units containing radioactive gamma-emitting sources with high activity and long half-life (usually 137Cs) are on the market. The characteristics of these "irradiators" allow their implementation in any laboratory with no need of structural shieldings. In spite of it, serious accidents (e.g., fire, fallings, etc.) which could imply hazards for the operating staff and even the general population, cannot be excluded. At the same time, the problem of long-term disposal of exhausted sources cannot be neglected. For these reasons, a new type of self-shielded irradiator was designed. It is equipped with an X-ray tube, operating at nearly 200-kV voltage, with 12-mA anodic current. The system is water- and oil-cooled and can work for a long time without thermal overloads. In this paper, the environmental and dosimetric measurements for beam characterization are reported. The system can produce beams with satisfactory characteristics for this specific problem. Moreover, its use may greatly reduce administrative radioprotection problems.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 045079078

Download citation: RISBibTeXText

PMID: 8346343


Related references

The micro-cell irradiator: a small volume gamma irradiator for on-site and special processing. Radiation Physics and Chemistry 57(3-6): 573-576, 2000

Development of a grain irradiator-optimum design of the irradiator. Radioisotopes 30(10): 545-550, 1981

A cesium-137 irradiator for small laboratory animals. Radiology 107(3): 641-644, 1973

Biological characterization of a novel in vitro cell irradiator. Plos One 12(12): E0189494-E0189494, 2017

Concept and building of an irradiator especially adapted for biological research. Journal Belge de Radiologie 46: 286-305, 1963

Using NanoDot dosimetry to study the RS 2000 X-ray biological irradiator. International Journal of Radiation Biology 89(12): 1094-1099, 2014

Characterization of an orthovoltage biological irradiator used for radiobiological research. Journal of Radiation Research 56(3): 485-492, 2016

Biological X-ray irradiator characterization for use with small animals and cells. Brazilian Journal of Medical and Biological Research 50(3): E5848-E5848, 2017

Conception and realization of an irradiator specially adapted to biological research. Jour Beige Radiol 46(3): 286-305, 1963

Development of a grain irradiator relation between dimension of the irradiator and grain flow in an irradiation region. Radioisotopes 30(8): 437-442, 1981

Clinical laboratory evaluation of the use of the MD-73M ultraviolet irradiator for the extracorporeal treatment of the patient's own blood in oral surgery. Stomatologiia 66(3): 53-56, 1987

Commissioning a small-field biological irradiator using point, 2D, and 3D dosimetry techniques. Medical Physics 38(12): 6754-6762, 2012

Cobalt-60 gamma-ray irradiator opens new doors to biological research at Davis. California Agric 16(3): 2-4, 1962

Transport integrated food irradiator canisters used with food irradiator and method of irradiating food us patent 4864595 september 5 1989. Official Gazette of the United States Patent & Trademark Office Patents 1106(1): 708, 1989

Biological effects of ionizing radiation on milk synthesis. I. A Co60 irradiator, Bossy Nova-mark 1. J. Dairy Sci, 48: 12, 1615-17, 1965