+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A new causal model of dental diseases associated with endocarditis



A new causal model of dental diseases associated with endocarditis



Annals of Periodontology 3(1): 184-196



Infective endocarditis (IE) is a serious disease that is associated with dental diseases and treatment. The objective of this study was to summarize the epidemiological information about IE and reevaluate previous causal models in light of this evidence. The world biomedical literature was searched from 1930 to 1996 for descriptive and analytic epidemiological studies of IE. Multiple searching strategies were performed on 9 databases, including MEDLINE, CATLINE, and WORLDCAT. Results show that: 1) the incidence of IE varies between 0.70 to 6.8 per 100,000 person-years: 2) the incidence of IE increases 20 fold with advancing age: 3) over 50% of all IE cases are not associated with either an obvious procedural or infectious event 3 months prior to developing symptoms; 4) about 8% of all IE cases are associated with periodontal or dental disease without a dental procedure: 5) the time from the diagnosis of heart valve deformities to the development of IE approaches 20 years: 6) the median time from identifiable procedures to the onset of IE symptoms is about 2 to 4 weeks: 7) the risk of IE after a dental procedure is probably in the range of 1 per 3,000 to 5,000 procedures: and 8) over 80% of all IE cases are acquired in the community, and the bacteria are part of the host's endogenous flora. The synthesis of these data demonstrates that IE is a disorder with the epidemiological picture of a chronic disease such as cancer, instead of an acute infectious disease, with a long latent period and possibly several definable intermediates or stages. A new causal model is proposed that includes early bacteremias that may "prime" the endothelial surface of the heart valves over many years, and a late bacteremia over days to weeks that allows adherence and colonization of the valve, resulting in the characteristic fulminant infection.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 045079295

Download citation: RISBibTeXText

PMID: 9722702

DOI: 10.1902/annals.1998.3.1.184


Related references

Etiopathogenesis of infective endocarditis: predisposing heart diseases and causal microorganisms. Revista Espanola de Cardiologia 51 Suppl 2: 11-15, 1998

Causal relationship between dental & heart diseases. I. La Riforma Medica 73(3): 61-63, 1959

Periodontal diseases and development of endocarditis following rat dental extractions. Journal of Dental Research 68(SPEC ISSUE JUNE): 990, 1989

Multidimensional causal model of dental caries development in low-income preschool children. Public Health Reports 110(5): 607-617, 1995

A causal model analysis of the quality of life in patients with cerebrovascular diseases at home. Okayama Igakkai Zasshi 108-109(11-12-1-2): 343-351, 1997

Compound treatments, transportability, and the structural causal model: the power and simplicity of causal graphs. Epidemiology 22(3): 378-381, 2011

Perceiving a strong causal relation in a weak contingency: further investigation of the evidential evaluation model of causal judgement. Quarterly Journal of Experimental Psychology. A, Human Experimental Psychology 55(1): 97-114, 2002

Model-based methods are valuable tools to identify causal genetic variants and to detect gene-environment interactions in complex diseases. American Journal of Human Genetics 73(5): 614, November, 2003

For the dental patient... Antibiotics before dental treatment. Preventing bacterial endocarditis. Journal of the American Dental Association 133(1): 127-127, 2002

Mutual medical-dental problems: prevention of subacute bacterial endocarditis associated with dental procedures. Connecticut Medicine 30(3): 174-177, 1966

Dental procedures and endocarditis prophylaxis: experiences from 108 dental practices. Scandinavian Journal of Dental Research 98(2): 144-148, 1990

Prevention of infective endocarditis associated with dental treatment and dental disease. New Zealand Medical Journal 93(682): 275-277, 1981

Preventing bacterial endocarditis: a statement for the dental professional. Council on Dental Therapeutics; American Heart Association. Journal of the American Dental Association 122(2): 87-92, 1991

Infective endocarditis Dental hygiene and non-dental exposures. Clinical Infectious Diseases 25(2): 369, 1997

Central venous catheter-induced endocarditis: human correlate of the animal experimental model of endocarditis. Reviews of Infectious Diseases 6(6): 783-790, 1984