+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

A review of evidence about factors affecting quality of pain management in sickle cell disease



A review of evidence about factors affecting quality of pain management in sickle cell disease



Clinical Journal of Pain 12(3): 180-193



To assess the evidence for pharmacological, behavioural, and interpersonal influences on quality of pain management in sickle cell disease. English-language reports from the research literature up to 1995, identified using Medline, Psychlit, and the Bath Information Data Service. Studies are reviewed that (a) reported quantitative clinical outcomes for particular analgesic methods used to treat painful episodes or (b) provide data on patient factors, interpersonal treatment factors, or levels of drug dependence in relation to pain management in sickle cell disease. Findings vary on the effectiveness of longer-acting opiates, patient-controlled or continuously infused analgesia, and behavioural analgesic techniques, with better results for trials where interpersonal aspects of pain management were also addressed. Risks for poorer pain management are greatest for patients in adverse social circumstances, who are more severely affected by painful episodes and who are poorly adjusted and have less effective personal strategies for coping with pain, but the limited evidence on drug dependence indicates very low levels by comparison with risk and exposure factors. Analgesic methods and approaches should continue to be developed and evaluated, but conflicting perceptions between patients and staff about pain that is reported and analgesia that is required probably contribute most to poor pain management in sickle cell disease. Promising areas for future research include the assessment of patients' everyday pain coping styles and patterns of drug use in relation to their hospital experiences of pain management, and the evaluation of psychological interventions to improve patients' styles and strategies for coping with pain.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 045106948

Download citation: RISBibTeXText

PMID: 8866159


Related references

Factors affecting hospital staff judgments about sickle cell disease pain. Journal of Behavioral Medicine 29(2): 203-214, 2006

Pain management and quality of life in sickle cell disease. Expert Review of Pharmacoeconomics and Outcomes Research 9(4): 347-352, 2009

Quality of life and pain management in sickle-cell disease. Pediatric Health 2(3): 377-391, 2008

Sickle cell disease pain management in adolescents: a literature review. Pain Management Nursing 16(2): 146-151, 2015

Acute pain in children and adults with sickle cell disease: management in the absence of evidence-based guidelines. Current Opinion in Hematology 16(3): 173-178, 2009

Evidence-based mini-review: Are systemic corticosteroids an effective treatment for acute pain in sickle cell disease?. Hematology. American Society of Hematology. Education Program 2010: 416-417, 2010

Effective pain management for patients with sickle cell vaso-occlusive crisis: A systematic review of barriers and interventions to improve quality. 2008

Review: Patient perceptions of crisis pain management in sickle cell disease: a cross-cultural study. Journal of Research in Nursing 5(3): 214-214, 2000

Understanding the causes of problematic pain management in sickle cell disease: evidence that pseudoaddiction plays a more important role than genuine analgesic dependence. Journal of Pain and Symptom Management 27(2): 156-169, 2004

Home management of sickle pain A daily diary study of analgesic usage by children and adolescents with sickle cell disease. Blood 98(11 Part 1): 493a, 2001

Using Quality Improvement Methods to Implement an Electronic Medical Record (EMR) Supported Individualized Home Pain Management Plan for Children with Sickle Cell Disease. Journal of Clinical Outcomes Management 21(5): 210-217, 2014

Evidence-Based Practice Standard Care for Acute Pain Management in Adults With Sickle Cell Disease in an Urgent Care Center. Quality Management in Health Care 26(2): 108-115, 2018

Pain intensity and home pain management of children with sickle cell disease. Issues in Comprehensive Pediatric Nursing 19(3): 183-195, 1996

The impact of a multidisciplinary pain management model on sickle cell disease pain hospitalizations. Pediatric Blood and Cancer 56(5): 789-793, 2011

Factors affecting prepubertal growth in homozygous sickle cell disease. Archives of Disease in Childhood 74(6): 502-506, 1996