+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

Beta blockers for CHF. Adrenergic blockade dramatically reduces morbidity and mortality

Beta blockers for CHF. Adrenergic blockade dramatically reduces morbidity and mortality

Postgraduate Medicine 109(3): 49-56

Several large clinical trials have shown that beta blockers can reduce morbidity and mortality in patients with CHF. Therefore, current guidelines for treatment of CHF now include beta blockers as standard therapy for patients with left ventricular systolic dysfunction (ejection fraction < or = 40%) and mild to moderate heart failure. Beta-blocker therapy for CHF should be started cautiously and increased gradually to avoid exacerbating symptoms of heart failure. At this time, data for therapy in patients with NYHA class I or IV symptoms are limited, and it is unclear whether all beta blockers confer benefit or whether some are better than others. Several trials are under way to answer these questions. Until more evidence is available, only those agents that have proved beneficial in mortality trials should be used to manage CHF.

(PDF emailed within 0-6 h: $19.90)

Accession: 045362925

Download citation: RISBibTeXText

PMID: 11265362

DOI: 10.3810/pgm.2001.03.875

Related references

Reduction of mortality, sudden death and non-fatal reinfarction with beta-adrenergic blockers in survivors of acute myocardial infarction: a new hypothesis regarding the cardioprotective action of beta-adrenergic blockade. American Journal of Cardiology 66(16): 66g-70g, 1990

The case for beta-adrenergic blockade as prophylaxis against perioperative cardiovascular morbidity and mortality. Archives of Surgery 136(3): 286-290, 2001

beta Blockade after myocardial infarction. Beta blockers have key role in reducing morbidity and mortality after infarction. Bmj 320(7234): 581-581, 2000

Treatment of Pre-Induction Tachycardia with beta-Adrenergic Blockade Reduces Mortality after CABG. Anesthesiology Abstracts of Scientific Papers Annual Meeting (2001): Abstract No A-250, 2002

Prophylactic perioperative beta-blockade reduces cardiac morbidity and mortality following non-cardiac surgery in patients at risk. Nederlands Tijdschrift Voor Geneeskunde 148(6): 268-275, 2004

Review: reduction in resting heart rate after taking beta-blockers or calcium-channel blockers reduce mortality and morbidity after MI. Evidence-Based Medicine 13(4): 112-112, 2008

Beta adrenergic receptor blockade : a self-limited phenomenon explaining the benignancy of acute poisoning with beta adrenergic inhibitors. Report of a series of 40 patients seen at the Fernand-Widal Toxicology Center, with a 0% mortality rate. La Semaine des Hopitaux 58(17): 1073-1076, 1982

Beta adrenergic blockade reduces utilitarian judgment. 2012

Beta adrenergic blockade reduces utilitarian judgement. Biological Psychology 92(2): 323-328, 2013

The effect of beta-blockers on morbidity and mortality associated with heart failure. American Journal of Managed Care 6(6 Suppl): S308-S312, 2000

The effects of beta blockers on morbidity and mortality in heart failure. Heart Failure Reviews 9(2): 115-121, 2004

Can beta blockers reduce cardiac morbidity and mortality in hypertension. Harefuah 117(7-8): 203-204, 1989

Perioperative beta-blockers for preventing surgery-related mortality and morbidity. Journal of Perioperative Practice 26(3): 30-31, 2016

Effects of alpha adrenergic blockers and beta adrenergic blockers on the actions of noradrenaline on body temperature in the new born guinea pig. Experientia (Basel) 33(8): 1083-1084, 1977