Changes of tissue oxygenation and relationship between oxygen delivery and consumption in patients with poor cardiac function undergoing valve replacement

Liu, L.; Zhou, J.; Chen, Q.

Hunan Yi Ke da Xue Xue Bao 23(3): 272-274

1998


ISSN/ISBN: 1000-5625
PMID: 10681757
Accession: 045481431

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Abstract
To study the relationship between oxygen delivery(DO2) and consumption(VO2) and tissue oxygenation in patients during cardiac valve replacement, DO2, VO2, arterial blood lactate (ABL) SvO2 were measured. The results showed a poor correlation between DO2 and VO2 and a normal tissue oxygenation before CPB. There was a good positive correlation between DO2 and VO2 within 20 h after the end of CPB(P < 0.01), and changes of ABL and SvO2 showed tissue hypoxia. The level of ABL in patients showing O2 supply-dependency was lower, and SvO2 was higher than those in 15 patients showing O2 supply-independency, respectively (P < 0.05). These data suggest that O2 supply-dependency was existed after the end of CPB, and there was a good correlation between O2 supply-dependency and ABL. It might not exclude tissue hypoxia in O2 supply-independency and normal level of SvO2.