Section 46
Chapter 45,498

Chemical composition of endotoxins produced by Fusobacterium necrophorum subsp. necrophorum and F. necrophorum subsp. funduliforme

Garcia, G.G.; Amoako, K.K.; Xu, D.L.; Inoue, T.; Goto, Y.; Shinjo, T.

Microbios 100(397): 175-179


ISSN/ISBN: 0026-2633
PMID: 10643665
Accession: 045497930

The endotoxins from two recently-classified subspecies of Fusobacterium, namely F. necrophorum subsp. necrophorum and F. necrophorum subsp. funduliforme, were compared. Chemical analysis of the isolated endotoxins revealed that they were clearly different. Distinct levels of polysaccharides were demonstrated. The endotoxins isolated were devoid of heptose and 3-deoxy-D-manno-octulosonate (KDO). The endotoxins of F. n. necrophorum and F. n. funduliforme contained lipid A in a ratio of 4:1 which may account for the variations in their virulence.

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