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A Fatal Case of Candida auris and Candida tropicalis Candidemia in Neutropenic Patient

Mohd Tap, R.; Lim, T.C.; Kamarudin, N.A.; Ginsapu, S.J.; Abd Razak, M.F.; Ahmad, N.; Amran, F.

Mycopathologia 183(3): 559-564

2018


ISSN/ISBN: 1573-0832
PMID: 29383574
DOI: 10.1007/s11046-018-0244-y
Accession: 045539611

We report a fatal case of Candida auris that was involved in mixed candidemia with Candida tropicalis, isolated from the blood of a neutropenic patient. Identification of both isolates was confirmed by amplification and sequencing of internal transcribed spacer and D1/D2 domain of large subunit in rRNA gene. Antifungal susceptibility test by E-test method revealed that C. auris was resistant to amphotericin B, anidulafungin, caspofungin, fluconazole, itraconazole and voriconazole. On the other hand, C. tropicalis was sensitive to all antifungal tested. The use of chromogenic agar as isolation media is vital in detecting mixed candidemia.

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