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Coatomer (COPI)-coated vesicles: role in intracellular transport and protein sorting


Coatomer (COPI)-coated vesicles: role in intracellular transport and protein sorting



Current Opinion in Cell Biology 9(4): 484-487



ISSN/ISBN: 0955-0674

PMID: 9261053

DOI: 10.1016/s0955-0674(97)80023-3

Coatomer-coated vesicles have been proposed to play a role in many distinct steps of intracellular transport. Coatomer potentially plays a role in forward transport from the endoplasmic reticulum to the Golgi apparatus and through the Golgi apparatus. It may also function in retrograde transport and in the endocytic pathway. There are limitations to the various approaches used to study the role of coatomer, and looking at these helps us to better define the questions that remain to be answered.

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Accession: 045555570

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Related references

Sec12p requires Rer1p for sorting to coatomer (COPI)-coated vesicles and retrieval to the ER. Journal of Cell Science 110: 991-1003, 1997

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