+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Contrast media for optical mammography

Contrast media for optical mammography

Der Radiologe 37(9): 749-755

Near infrared imaging is a non-invasive imaging modality which uses light of a spectral range between 650 and 1000 nm for tissue transillumination. Near infrared photons can penetrate by diffusion into tissue up to several centimeters due to low absorption by intrinsic chromophors (e.g. hemoglobine). During the last years optical mammography has become field of growing interest. Several prototypes of near infrared scanners have been developed for clinical studies in order to obtain transillumination images of the breast. The results indicated, that discrimination of tumors located up to several centimeters below the tissue surface (e.g. breast tumors) from surrounding healthy tissue did not succeed with sufficient specificity. The diagnostic potential of near infrared imaging can be enhanced using dyes as contrast agents. Specially designed cyanine dye derivatives are potential contrast agents because of their suitable optical properties and pharmacokinetic behaviour leading to an increased tumor fluorescence in animals after intravenous injection.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 045639303

Download citation: RISBibTeXText

PMID: 9424621

Related references

Digital mammography using iodine-based contrast media: initial clinical experience with dynamic contrast medium enhancement. Investigative Radiology 40(7): 397-404, 2005

Intraoperatively assessed optical properties of malignant and healthy breast tissue used to determine the optimum wavelength of contrast for optical mammography. Journal of Biomedical Optics 9(6): 1129-1136, 2004

Contrast media in MR mammography. Aktuelle Radiologie 7(2): 86-92, 1997

Our experience in the field of mammography without contrast media. Acta Chirurgica Italica 23(1): 11-29, 1967

Contrast media and metformin: guidelines to diminish the risk of lactic acidosis in non-insulin-dependent diabetics after administration of contrast media. ESUR Contrast Media Safety Committee. European Radiology 9(4): 738-740, 1999

Combined optical imaging and mammography of the healthy breast: optical contrast derived from breast structure and compression. IEEE Transactions on Medical Imaging 28(1): 30-42, 2009

Mammography : X-Ray Examination of Milk Ducts by Using Contrast Media. Rev. med. lat. amer 24: 999-1016, 1939

The radial scar in contrast media-enhanced MR mammography. Rofo 172(10): 817-823, 2000

Do shorter wavelengths improve contrast in optical mammography?. Physics in Medicine and Biology 49(7): 1203-1215, 2004

A search for optimal x-ray spectra in iodine contrast media mammography. Physics in Medicine and Biology 50(13): 3143-3152, 2005

Sources of absorption and scattering contrast for near-infrared optical mammography. Academic Radiology 8(3): 211-218, 2001

Identification and quantification of intrinsic optical contrast for near-infrared mammography. Photochemistry & Photobiology. 67(1): 4-14,., 1998

Macromolecular contrast media for MR mammography. A new approach to characterizing breast tumors. Der Radiologe 37(9): 733-740, 1997

New contrast media designed for x-ray energy subtraction imaging in digital mammography. Investigative Radiology 38(9): 602-608, 2003

Near-infrared optical mammography for breast cancer detection with intrinsic contrast. Annals of Biomedical Engineering 40(2): 398-407, 2012