Dolastatin 3 and two novel cyclic peptides from a palauan collection of Lyngbya majuscula
Mitchell, S.S.; Faulkner, D.J.; Rubins, K.; Bushman, F.D.
Journal of Natural Products 63(2): 279-282
2000
ISSN/ISBN: 0163-3864 PMID: 10691729 DOI: 10.1021/np990353f
Accession: 045827141
A collection of Lyngbya majuscula from Palau contained the peptides dolastatin 3 (1), homodolastatin 3 (2), and kororamide (3), together with aplysiatoxin (4), debromoaplysiatoxin (5), and oscillatoxin A (6). The structures of the new peptides homodolastatin 3 (2) and kororamide (3) were determined by interpretation of spectroscopic data and chemical degradation.