Section 46
Chapter 45,837

Draize test and alternative methods for evaluating irritation from chemical substances

Moskalewski, S.; Mystkowska, E.T.; Kiss, E.

Roczniki Panstwowego Zakladu Higieny 46(2): 163-168


ISSN/ISBN: 0035-7715
PMID: 8533034
Accession: 045836219

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The eye irritancy test in rabbits (Draize test) is currently the method used to evaluate the hazard or safety of chemical substances. To reduce the need for animal testing some new procedures as alternative were elaborated. We present a review of method used as well as evaluation of sensitivity and repeatability of alternative tests applied in laboratories of European Economic Communities.

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