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Effect of Pichia anomala killer toxin on Candida albicans



Effect of Pichia anomala killer toxin on Candida albicans



Medical Mycology 36(4): 199-204



The effect of a Pichia anomala killer toxin upon a Candida albicans-sensitive strain was studied. Yeast and hyphae, after treatment with the toxin, were less capable of uptaking either [3H]-uridine or [35S]-methionine. In addition, the hyphal form of the fungus appeared to be less capable of DNA synthesis after toxin treatment. No effect of the killer toxin was shown upon a natural resistant mutant of the source strain. These data suggest that, similar to other killer yeast toxins, the toxin of P. anomala can produce a number of quantifiable effects upon sensitive C. albicans cells.

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Accession: 045868987

Download citation: RISBibTeXText

PMID: 9776835

DOI: 10.1080/02681219880000301


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