+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn

+ Translate
+ Recently Requested

Effect of folic acid supplements on homocysteine concentration in plasma of gestating sows

Effect of folic acid supplements on homocysteine concentration in plasma of gestating sows

Archiv für Tierernahrung 54(1): 81-85

An experiment comprising 19 German Landrace sows was established to evaluate the effect of folic acid supplements (10 mg/kg concentrate) on homocysteine and folic acid concentration in plasma and serum, respectively, of highly pregnant sows as compared to an unsupplemented control (basal diet contained 0.62 mg folic acid/kg concentrate). Blood samples were taken between day 75 and 110 of gestation for homocysteine analysis and on day 100 of gestation for folic acid determination. Due to the folic acid supplements serum folic acid concentration increased significantly (104 nmol/l in controls and 140 nmol/l in supplemented sows). In contrast, homocysteine concentration in the plasma was not significantly influenced by folic acid supplements (16.6 mumol/l in controls and 15.2 mumol/l in supplemented sows). Further investigations seem to be necessary to clarify the physiology of homocysteine metabolism in swine.

(PDF emailed within 1 workday: $29.90)

Accession: 045879154

Download citation: RISBibTeXText

PMID: 11851018

Related references

Effect of folic acid supplements on homocysteine concentration in plasma of gestating sows. Archives of Animal Nutrition 54(1): 81-85, 2001

Effect of different folic acid supplements on homocysteine in plasma of sows. Vitamine und Zusatzstoffe in der Ernahrung von Mensch und Tier: 7 Symposium Jena/Thuringen, Germany, 22 und 23 September 1999: 338-341, 1999

Effect of supplementation with folic acid throughout pregnancy on plasma homocysteine concentration. Thrombosis Research 114(1): 25-27, 2004

Plasma homocysteine concentration and its relationship with the development of preeclampsia. Effect of prenatal administration of folic acid. Investigacion Clinica 46(2): 187-195, 2005

Effects of intervention therapy of methylcobalamin and folic acid on plasma homocysteine concentration and homocysteine thiolactonases/paraoxonase activity in patients with type 2 diabetes mellitus. Zhonghua Yi Xue Za Zhi 87(4): 256-258, 2007

Association between adherence to folic acid supplements and serum folate, and plasma homocysteine among hemodialysis patients. Journal of Renal Nutrition 21(3): 246-256, 2011

A folate-rich diet is as effective as folic acid from supplements in decreasing plasma homocysteine concentrations. International Journal of Medical Sciences 2(2): 58-63, 2005

Lowering plasma homocysteine with vitamins B6, B12, and folic acid. Effect on lipids concentration in patients with secondary hyperlipoproteinemia type IV, with and without Lovastatina treatment. Archivos Latinoamericanos de Nutricion 56(1): 36-42, 2006

Folic acid supplements lower plasma homocysteine and improve flow-mediated endothelial function in healthy adults. Netherlands Journal of Medicine 52(SUPPL ): S14, April, 1998

Plasma homocysteine in acute myocardial infarction: Homocysteine-lowering effect of folic acid. Journal of Internal Medicine 237(4): 381-388, 1995

The role of folic acid in the nutrition of gestating and lactating primiparous sows. Livestock Production Science 32(2): 131-148, 1992

Effects of multivitamins and low-dose folic acid supplements on flow-mediated vasodilation and plasma homocysteine levels in older adults. American Heart Journal 148(3): E11-E11, 2004

Effect of daily vitamin B-12 and folic acid supplementation on fracture incidence in elderly individuals with an elevated plasma homocysteine concentration: B-PROOF, a randomized controlled trial. American Journal of Clinical Nutrition 100(6): 1578-1586, 2015

The effect of folic acid supplements during the feeding of pregnant sows on the mortality of fetuses. Medycyna Weterynaryjna 52(1): 51-53, 1996