+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Enterogastric reflux mimicking gallbladder disease: detection, quantitation and potential significance

Enterogastric reflux mimicking gallbladder disease: detection, quantitation and potential significance

Journal of Nuclear Medicine Technology 27(3): 207-214

Visualization of enterogastric reflux (EGR) may be present during hepatobiliary imaging. Reflux of bile may damage the gastric mucosa, altering its function, and cause such symptoms as epigastric pain, heartburn, nausea, intermittent vomiting and abdominal fullness. These symptoms also are associated with gallbladder disease. The aim of this study was to quantitate the EGR index (EGRI) and to determine if a difference exists in normal and abnormal responses using standard cholecystokinin (CCK)-augmented hepatobiliary imaging. This study used 129 patients. LAO dynamic data on a 128 x 128 matrix at a rate of 1 frame/min were obtained. After the gallbladder ejection fraction (GBEF) was determined, the EGRI (%) was calculated by relating the counts in the gastric ROI to the counts in the hepatobiliary ROI at a specified time. The results were compared with the patient's final clinical diagnosis. Normal responders (GBEF > or = 35%) had a higher EGRI than abnormal responders with a P = 0.001 EGR observed in 75 patients (58.1%). Significant reflux (EGRI > or = 14.2% at 15 min) was observed in 29 additional patients (22.5%). Patients with EGRI > or = 24.5% showed a strong association with the pathophysiologic syndrome of gastritis, alkaline reflux, gastric ulcer and gastro esophageal reflux disease. There was no EGR observed in the remaining 25 patients (19.4%). This simple addition to the CCK-augmented hepatobiliary imaging may both detect and quantitate abnormal EGR as the cause of the patient's symptoms in the presence of a normal GBEF result, and/or those patients with risk factors for gastritis.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 045970863

Download citation: RISBibTeXText

PMID: 10512476

Related references

Enterogastric reflux mimicking gallbladder visualization in acute cholecystitis. Journal of Nuclear Medicine 26(8): 961-962, 1985

Enterogastric reflux in normal subjects and patients with Bilroth II gastroenterostomy. Measurement of enterogastric reflux. Gastroenterology 77(5): 1027-1033, 1979

The relationship between enterogastric reflux of bile and gallbladder function. Nuclear Medicine Communications 6(9): 576, 1985

The relationship between gallbladder motility and the presence of enterogastric reflux. Nuclear Medicine Review. Central and Eastern Europe 5(1): 25-28, 2003

Gallbladder function and fasting enterogastric bile reflux. Nuclear Medicine Communications 10(3): 193-198, 1989

Evaluation of enterogastric reflux in relation to functional status of the gallbladder. Acta Chirurgica Iugoslavica 48(3): 49-53, 2002

A composite score of enterogastric reflux quantitation on 99mTc-HIDA scintigraphy. Hepato-Gastroenterology 42(6): 847-850, 1995

Enterogastric reflux after various types of antiulcer gastric surgery: quantitation by 99mTc-HIDA scintigraphy. Gastroenterology 101(4): 991-998, 1991

Enterogastric reflux detection with technetium-99m IDA. Clinical Nuclear Medicine 10(8): 550-552, 1985

Incidence and significance of enterogastric reflux during morphine-augmented cholescintigraphy. Clinical Nuclear Medicine 17(12): 926-928, 1992

The presence and significance of Helicobacter pylori in patients with enterogastric reflux. Acta Chirurgica Iugoslavica 46(1-2): 53-56, 2000

Enterogastric reflux measurement by contemporary acid and reflux test. Digestive Surgery 1(2-3): 87-88, 1984

Gastroesophageal reflux scintigraphy with radioactive capsules a new technique for detection and quantitation of reflux. European Journal of Nuclear Medicine 16(4-6): 344-348, 1990

Significance of the gallbladder in the regulation of duodenogastric reflux. Zeitschrift für Gastroenterologie 25 Suppl 3: 15-21, 1987

Clinical studies on vesicoureteral reflux--significance of detection of the "missing VUR" (vesico-ureteral reflux). Nihon Hinyokika Gakkai Zasshi. Japanese Journal of Urology 78(10): 1776-1783, 1987