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Epidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leukaemia virus in serum pools



Epidemiological evaluation of a monoclonal ELISA detecting antibodies against bovine leukaemia virus in serum pools



Epidemiology and Infection 113(3): 563-569



Sensitivity, specificity and predictive values of an enzyme-linked immunosorbent assay (ELISA) for detecting antibodies against bovine leukaemia virus (BLV) were evaluated using a representative sample of 145 serum pools, comprising from 3 to 48 individual sera. The sample was constituted according to the frequency distribution of the negative and positive pools analysed during a screening involving the whole cattle population of Belgium. Sensitivity and specificity were estimated to 88.9% and 100% and the predicted negative and positive values were 99.9% and 100%, respectively. These results indicate the use of serum pools is suitable for the detection of BLV infected herds in eradication campaigns.

Accession: 045976307

Download citation: RISBibTeXText

PMID: 7995365

DOI: 10.2307/3864328


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