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Evaluation of drug side effects over a year in a cardiology service

Evaluation of drug side effects over a year in a cardiology service

Therapie 48(3): 259-262

An intensive pharmacovigilance survey was carried out over the course of 1 year in cardiology department which revealed 64 reports of adverse drug reactions among 61 hospitalised patients, giving an overall incidence of 2.3%. Most of the patients in whom adverse drug reactions were recorded were elderly and female. The most common adverse events were cardiovascular (72%) and haemorrhagic (9%), and related to drugs given for the treatment of cardiovascular disorders. The symptoms originating from drug therapy were dominated by sinus arrhythmias (25 cases), linked to drugs co-administered that have potentially similar cardiac pharmacodynamic effects. Seven cases of "torsades de pointe" were also observed.

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Accession: 046009371

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PMID: 8140567

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