+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Evaluation of giant-cell deposits on foldable intraocular lenses after combined cataract and glaucoma surgery



Evaluation of giant-cell deposits on foldable intraocular lenses after combined cataract and glaucoma surgery



Journal of Cataract and Refractive Surgery 26(6): 817-823



To compare the incidence of inflammatory giant-cell deposits (IGCDs) on various foldable intraocular lenses (IOLs) after combined cataract and glaucoma surgery. The Phillips Eye Institute, Minneapolis, Minnesota, USA. In this prospective randomized clinical trial, 128 patients were randomized to receive a single-piece, first-generation silicone lens (n = 36); a 3-piece acrylic lens (n = 40); or 3-piece, second-generation silicone lens (n = 52). All patients had combined phacoemulsification and trabeculectomy with mitomycin-C by 1 surgeon using a standardized technique. Dilated biomicroscopy was used to identify and quantitate IGCDs on the surface of the IOLs using a 6-point grading scale. Inflammatory giant-cell deposits were identified on 21 of 128 IOLs. Lens design was the most significant risk factor for deposit formation (P =.004). Inflammatory giant-cell deposits were most common in the first-generation silicone plate lens group (33%), less common in the acrylic lens group (15%), and least common in the 3-piece, second-generation silicone group (5.8%). Density of the deposits was significantly greater on the plate lens than the acrylic or the 3-piece silicone lenses (P <.0001). Although IOL design was the most significant risk factor for IGCD formation, other significant risk factors included intraoperative pupil stretch (P =.02) and preoperative miotic use (P =.04). Inflammatory giant-cell deposit formation was significantly greater on first-generation silicone plate IOLs than on acrylic or second-generation silicone IOLs. The deposits were somewhat more common on acrylic IOLs than on second-generation silicone IOLs. However, this difference was not clinically or statistically significant.

(PDF emailed within 0-6 h: $19.90)

Accession: 046010081

Download citation: RISBibTeXText

PMID: 10889425

DOI: 10.1016/s0886-3350(00)00308-4


Related references

Cost effectiveness of foldable multifocal intraocular lenses compared to foldable monofocal intraocular lenses for cataract surgery. British Journal of Ophthalmology 88(9): 1163-1168, 2004

Comparative results of combined procedures for glaucoma and cataract: I. Extracapsular cataract extraction versus phacoemulsification and foldable versus rigid intraocular lenses. Ophthalmic Surgery and Lasers 28(7): 539-550, 1997

Combined surgery for cataract and glaucoma: phacoemulsification, foldable intraocular lens implantation and viscocanalostomy. Zhejiang Da Xue Xue Bao. Yi Xue Ban 33(1): 73-76, 2004

Refractive outcomes of foldable silicone intraocular lenses versus pmma intraocular lensesin paediatric cataract surgery. ARVO Annual Meeting Abstract Search & Program Planner : Abstract No 263, 2003

The use of different types of foldable acrylic intraocular lenses after cataract surgery using the phacoemulsification in dogs. Medvep (revista Cientifica De Medicina Veterinarianos Animais E Animais De Estimacao): 260-267, 2008

Combined phacoemulsification, foldable intraocular lens implantation and trabeculectomy for cataract patients with glaucoma. Chinese Journal of Ophthalmology 36(5): 330-333, 2002

PARS PLANA VITRECTOMY COMBINED WITH CATARACT EXTRACTION: A Comparison of Surgical Outcomes Using Single-Piece and Multipiece Foldable Intraocular Lenses. Retina 35(6): 1059-1064, 2015

A quantitative study of anterior chamber angle with ultrasound biomicroscopy after cataract surgery with phacoemulsification and foldable intraocular lenses implantation. Chinese Journal of Ophthalmology 40(2): 94-96, 2004

Study of anterior chamber configuration with panoramic ultrasound biomicroscopy after cataract surgery with phacoemulsification and foldable intraocular lenses implantation. Chinese Journal of Ophthalmology 44(4): 301-305, 2008

Comparison of PMMA, foldable silicone and foldable acrylic hydrophobic intraocular lenses in combined phacoemulsification and trabeculectomy. Arquivos Brasileiros de Oftalmologia 68(1): 29-35, 2005

Evaluation of Corneal Endothelial Cell Reduction Rates After Combined Glaucoma and Cataract Surgery and After Glaucoma Surgery Alone. ARVO Annual Meeting Abstract Search & Program Planner : Abstract No 1080, 2002

The effect of heparin-coated intraocular lenses on intraocular pressure following combined trabeculectomy and cataract surgery. Acta Ophthalmologica Scandinavica 75(4): 437-440, 1997

Postoperative intraocular pressure iop following cataract or combined cataract filtering surgery in open angle glaucoma. Investigative Ophthalmology & Visual Science 29(ABSTR ISSUE): 275, 1988

Postoperative intraocular pressure rise in open-angle glaucoma patients after cataract or combined cataract-filtration surgery. Ophthalmology 96(5): 579-584, 1989

Cataract and combined cataract/glaucoma surgery as intraocular pressure-reducing procedure in eyes with relative anterior microphthalmos. Klinische Monatsblatter für Augenheilkunde 222(3): 206-210, 2005