+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Evaluation of preoperative diagnosis of primary hyperparathyroidism--special reference to normocalcemic cases



Evaluation of preoperative diagnosis of primary hyperparathyroidism--special reference to normocalcemic cases



Nihon Hinyokika Gakkai Zasshi. Japanese Journal of Urology 84(3): 546-551



Since the opening of our clinic 117 years before, we have treated 62 cases of primary hyperparathyroidism (PHPT), among which there were 6 cases (1 male, 5 females) whose calcium levels fell within the normal range. However, in all these cases the serum ionized calcium (Ca++) levels and the serum ionized calcium/calcium ratio (Ca++/Ca ratio) were high. Moreover, in comparing them with hypercalcemic patients (56 cases), the serum Ca++ levels were significantly lower, but the (Ca++/Ca ratio) was significantly higher. Also, the excised weight of 606.1 +/- 520.3 mg was significantly smaller than that of hypercalcemic patients, which was 1,967.9 +/- 2,086.3 mg. Preoperative locations showed significantly lower levels in comparison with hypercalcemic patients by all methods including computed tomography (CT), ultrasonography, scintigraphy, and magnetic resonance imaging (MRI). In normocalcemic patients following parathyroidectomy, although the decrease in serum calcium levels was not significant, the serum Ca++ levels and the Ca++/Ca ratio decreased significantly, so that not only are they useful parameters for preoperative diagnosis of PHPT, but they are also considered necessary and indispensable for observation of the post-operative course and judging therapeutic effects including the operation. Based on our study we concluded that in multiple and recurrent stone formers with normal range of serum Ca levels, regardless of the presence or absence of local diagnosis, if the serum Ca++ level and Ca++/Ca ratio are high, existence of primary hyperparathyroidism must be suspected, and adequate treatments should be instituted promptly.

(PDF emailed within 1 workday: $29.90)

Accession: 046012588

Download citation: RISBibTeXText

PMID: 8515642


Related references

Preoperative and postoperative evaluation of patients with normocalcemic primary hyperparathyroidism. Surgical Forum 21(4): 96-98, 1970

Normocalcemic, subclinical, asymptomatic primary hyperparathyroidism in patients with goiter or papillary thyroid cancer--preliminary report. Normocalcemic primary hyperparathyroidism and thyroid pathology. Wiadomosci Lekarskie 60(5-6): 228-230, 2007

The evaluation of vitamin D status in normocalcemic primary hyperparathyroidism. European Journal of Internal Medicine 24(1): E8-E8, 2013

Hyperparathyroidism; an analysis of ten cases with special reference to earlier diagnosis. American Journal of Surgery 76(4): 404-411, 1948

Evaluation of coronary calcium score in patients with normocalcemic primary hyperparathyroidism. Vascular Health and Risk Management 13: 225-229, 2017

The arthritis of hemochromatosis. A review of 25 cases with special reference to chondrocalcinosis, and a comparison with patients with primary hyperparathyroidism and controls. Clinical Rheumatology 5(3): 317-324, 1986

A case of primary hyperparathyroidism associated with thyroid carcinoma with special reference to pre-operative diagnosis of parathyroid adenoma by scintigraphy. Horumon to Rinsho. Clinical Endocrinology 30(1): 47-51, 1982

Brown tumors of the anterior skull base as the initial manifestation of true normocalcemic primary hyperparathyroidism: report of three cases and review of the literature. Turkish Neurosurgery 23(2): 260-266, 2013

Indication of nephrostomy and ureterostomy for cases of intrapelvic carcinomas: with special reference to observations on critical preoperative evaluation. Nihon Hinyokika Gakkai Zasshi. Japanese Journal of Urology 62(1): 58-63, 1971

Evaluation of preoperative serum concentrations of ionized calcium and parathyroid hormone as predictors of hypocalcemia following parathyroidectomy in dogs with primary hyperparathyroidism: 17 cases (2001-2009). Journal of the American Veterinary Medical Association 241(2): 233-236, 2012

Preoperative localization diagnosis of parathyroid adenomas in 72 cases of primary hyperparathyroidism by selective catheterization of neck veins and parathyroid hormone determination. Schweizerische Medizinische Wochenschrift 113(17): 636-640, 1983

Normocalcemic primary hyperparathyroidism. Polski Tygodnik Lekarski 34(16): 625-626, 1979

Normocalcemic primary hyperparathyroidism. Journal of Clinical Densitometry 16(1): 33-39, 2013

Different PTH response to oral peptone load and oral calcium load in patients with normocalcemic primary hyperparathyroidism, primary hyperparathyroidism, and healthy subjects. European Journal of Endocrinology 167(4): 491-497, 2012

Diagnosis and treatment of primary thoracic tumors - with special reference to our 13 cases. Nihon Kyobu Geka Gakkai 22(5): 460-462, 1974