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Failure of maternal antibodies to protect young turkey poults against challenge with turkey rhinotracheitis virus


Failure of maternal antibodies to protect young turkey poults against challenge with turkey rhinotracheitis virus



Avian Diseases 41(4): 968-971



ISSN/ISBN: 0005-2086

PMID: 9454934

DOI: 10.2307/1592354

Groups of turkey poults with high levels of maternal antibodies (MA+) to turkey rhinotracheitis virus (TRTV) were challenged with virulent TRTV at 1, 5, and 10 days of age. A maternal antibody-free group (MA-) was also challenged at 1 day of age. Before each challenge, levels of maternal antibodies to TRTV were measured by enzyme-linked immunosorbent assay. Clinical signs were scored for each group. Unchallenged poults showed no signs. Respiratory signs in poults infected at 10 days of age resembled those seen in MA- birds infected at 1 day of age but both were more severe than in MA+ birds infected at 1 day of age, when the maternal antibodies were highest. However, overall, the presence of high levels of maternal antibodies did not prevent the development of clinical disease.

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Accession: 046071001

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