+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Forensic validation of the STR systems SE 33 and TC 11

Forensic validation of the STR systems SE 33 and TC 11

International Journal of Legal Medicine 105(6): 315-320

Population studies on Caucasians from northwest Germany were carried out using the short tandem repeat (STR) systems SE 33 (Locus: ACTBP2) and TC 11 (Locus: 11p15.5). After electrophoresis in PAG 26 alleles could be identified for SE 33 in a sample size of 180 unrelated individuals and 6 alleles were found for TC 11 in 110 individuals. The combined mean exclusion chance for both systems was 0.96 and the discrimination index 0.999. No significant deviations from Hardy-Weinberg equilibrium could be demonstrated. In a small sample of families (SE 33 - n = 21; TC 11 - n = 30) no new mutations could be found. Positive and reproducible results for both STRs could be obtained from 50 pg template DNA.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 046114623

Download citation: RISBibTeXText

PMID: 8518197

DOI: 10.1007/bf01222114

Related references

Validation of short tandem repeats (STRs) for forensic usage: performance testing of fluorescent multiplex STR systems and analysis of authentic and simulated forensic samples. Journal of Forensic Sciences 46(3): 647-660, 2001

The validation of forensic DNA extraction systems to utilize soil contaminated biological evidence. Legal Medicine 17(4): 232-238, 2015

Validation and comparative study of the AmpFlSTR IdentifilerTM and the PowerPlex TM 16 STR multiplex systems for forensic casework using capillary electrophoresis. Forensic Science International 136(Suppl 1): 54-55, 2003

Two discriminatory multiplex STR systems for forensic identification Validation and Canadian casework experience with automated fluorescent technologies. Olaisen, B , Brinkmann, B , Lincoln, P J International Congress Series; Progress in Forensic Genetics, 7 433-435, 1998

Scientific Working Group for Forensic Toxicology (SWGTOX) standard practices for method validation in forensic toxicology. Journal of Analytical Toxicology 37(7): 452-474, 2013

DNA Commission of the International Society for Forensic Genetics: Recommendations on the validation of software programs performing biostatistical calculations for forensic genetics applications. Forensic Science International. Genetics 25(): 191-197, 2016

Clinical validation of the CANFOR scale (Camberwell Assessment of Need-Forensic version) for the needs assessment of people with mental health problems in the forensic services. Actas Espanolas de Psiquiatria 38(3): 129-137, 2011

Forensic focused treatment planning: a new standard for forensic mental health systems. Cns Spectrums 20(3): 250-253, 2015

Computer-assisted systems for forensic pathology and forensic toxicology. Journal of Forensic Sciences 41(5): 830-836, 1996

Wearable Health Devices-Vital Sign Monitoring, Systems and Technologies. Sensors 18(8):, 2018

Identifying and measuring juror pre-trial bias for forensic evidence development and validation of the Forensic Evidence Evaluation Bias Scale. Psychology, Crime & Law 18(9): 797-815, 2012

Forensic Validation of the Goldeneye™ DNA ID 25A Kit. Fa Yi Xue Za Zhi 31(4): 284-286, 2015

Forensic validation of goldeneye? DNA ID 26Y system. Fa Yi Xue Za Zhi 30(6): 446-51 455, 2014

ISBT - Guidelines for validation and maintaining the validation state of automated systems in blood banking. Vox Sanguinis 85(Suppl. 1): S1, 2003