+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Hand-assisted laparoscopic donor hepatectomy for living related transplantation in the porcine model



Hand-assisted laparoscopic donor hepatectomy for living related transplantation in the porcine model



Surgical Laparoscopy, Endoscopy and Percutaneous Techniques 12(4): 232-237



Use of a minimally invasive approach for donor nephrectomy has proven to be safe and feasible and has increased the pool of donors for living related renal transplantation. A porcine study to assess the safety and feasibility of performing laparoscopic donor hepatectomy was performed, with potential application to human liver donors for living related liver transplantation. Of the 10 50-kg pigs used, 2 underwent an open left lateral segmentectomy to define the pig anatomy. Two subsequent pigs underwent a laparoscopic liver resection to refine the technique. Subsequently, under sterile conditions, six pigs underwent laparoscopic liver resection with use of a hand-assisted technique for long-term study. Diameters and lengths of hepatic vessels and ducts were measured. Operative blood loss, operative time, and warm ischemia duration were noted. Biopsies of the resected specimens were done to look for ischemia. There was one operative death in the group with chronic liver failure, due to stapler misfire and hemorrhage from the left hepatic vein. The only instance of morbidity was a wound infection. The resected liver had minimal warm ischemia time and microscopic changes, which led us to believe that the organ was suitable for transplantation. We believe that this long-term study establishes the feasibility of this procedure.

(PDF emailed within 0-6 h: $19.90)

Accession: 046211036

Download citation: RISBibTeXText

PMID: 12193816

DOI: 10.1097/00129689-200208000-00006


Related references

Hand-assisted laparoscopic donor hepatectomy in a porcine model. Gastroenterology 116(4 PART 2): A1314, April, 1999

Renal vein extension during living-donor kidney transplantation in the era of hand-assisted laparoscopic living-donor nephrectomy. Transplantation 99(4): 786-790, 2015

Re: Renal vein extension during living-donor kidney transplantation in the era of hand-assisted laparoscopic living-donor nephrectomy. Journal of Urology 193(3): 950-951, 2015

Simultaneous pancreas-kidney transplantation from living donor using hand-assisted laparoscopic donor surgery: single-center experience. Transplantation Proceedings 47(4): 1096-1098, 2016

Early and late graft function after laparoscopic hand-assisted donor nephrectomy for living kidney transplantation: comparison with open donor nephrectomy. Urologia Internationalis 84(1): 61-66, 2010

The feasibility and effectiveness of a hand-assisted laparoscopic splenectomy for hypersplenism in patients after living-donor liver transplantation. Surgical Laparoscopy, Endoscopy and Percutaneous Techniques 19(6): 484-487, 2011

Elective living donor liver transplantation by hybrid hand-assisted laparoscopic surgery and short upper midline laparotomy. Surgery 150(5): 1002-1005, 2011

Single-port laparoscopy-assisted donor right hepatectomy in living donor liver transplantation: sensible approach or unnecessary hindrance?. Transplantation Proceedings 44(2): 347-352, 2012

Hand-assisted laparoscopic living-donor nephrectomy as an alternative to traditional laparoscopic living-donor nephrectomy. American Journal of Transplantation 2(10): 983-988, 2002

Donor complications following laparoscopic compared to hand-assisted living donor nephrectomy: an analysis of the literature. Journal of Transplantation 2010: 825689, 2010

Impact of hand-assisted laparoscopic living donor nephrectomy on donor's quality of life, emotional, and social state. Transplantation Proceedings 42(5): 1487-1491, 2010

Laparoscopic living donor hepatectomy for liver transplantation in children. Lancet 359(9304): 392-396, 2002

Laparoscopic living donor hepatectomy for pediatric liver transplantation. Acta Chirurgica Belgica 109(4): 559-562, 2009

Single-center analysis of living donor nephrectomy: hand-assisted laparoscopic, pure laparoscopic, and traditional open. Progress in Transplantation 12(3): 206-211, 2002

Comparison of renal function recovery in donor and recipient after living donor nephrectomy: Hand-assisted laparoscopic vs. open procedures. European Urology Supplements 7(3): 195, 2008