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Hemiballismus disclosing cerebral toxoplasmosis and acquired immunodeficiency syndrome



Hemiballismus disclosing cerebral toxoplasmosis and acquired immunodeficiency syndrome



Revue Neurologique 149(6-7): 421-423



A 33-year-old Saudi woman presented with right hemiballismus of recent onset. Brain CT showed a left thalamo-subthalamic lesion which was thought initially to be a metastasis or a tuberculoma. The presence of severe subacute diarrhea, multiple lymphadenopathies and lymphopenia suggested an acquired immunodeficiency syndrome (AIDS). Tests for HIV-1 infection were positive and, despite the absence of antitoxoplasma antibodies in the serum, antitoxoplasmic treatment by pyrimethamine and sulfadiazine was given. One and a half month later, both abnormal movements and CT images had disappeared. The probable source of HIV infection was imported packed red blood cells received by the patient 5 years earlier. Toxoplasmic brain abscess associated with AIDS should be considered as a possible cause of hemiballismus in young adult even in the regions where AIDS is still infrequent.

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Accession: 046233063

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PMID: 8303164


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