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Host range of influenza viruses and their receptor binding specificities



Host range of influenza viruses and their receptor binding specificities



Nihon Rinsho. Japanese Journal of Clinical Medicine 55(10): 2640-2647



Host-range of influenza viruses are established by many factors in nature such as the quantitative, qualitative aspects of the viral receptor, the permissive and non permissive states of host-cell condition, and also the antibody and inhibitor pressure present in the host. Influenza virus hemagglutinin recognizes specific sialyl-sugar chains of the host cell membranes. In this paper, the structure and function of sialyl-sugar chains as influenza virus receptors are described in relation to the variation of influenza viruses and the molecular evolution of influenza virus hemagglutinin.

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Accession: 046274886

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PMID: 9360384


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