+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

How much contrast is enough?. Dependence of enhancement on field strength and MR pulse sequence

How much contrast is enough?. Dependence of enhancement on field strength and MR pulse sequence

European Radiology 7(Suppl. 5): 276-280

The overwhelming majority of published studies defining the clinical utility of gadolinium administration for neuroimaging have been performed at high field using conventional spin-echo imaging. Concerning the issue of field strength, several investigations have now shown that for a given dose of contrast, enhancement is less apparent at low field than at high field. Concerning the issue of pulse sequence, there is now convincing clinical and experimental evidence that all T1-weighted sequences are not equal in demonstrating contrast enhancement. Specifically, T1-weighted spoiled gradient-echo sequences do not show the same degree of visually apparent contrast enhancement compared to conventional spin-echo sequences. The use of magnetization transfer techniques which demonstrate areas of enhancement unseen on conventional pulse sequences is also addressed.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 046280086

Download citation: RISBibTeXText

PMID: 9370559

DOI: 10.1007/pl00006908

Related references

Field strength and dose dependence of contrast enhancement by gadolinium-based MR contrast agents. European Radiology 9(5): 998, 1999

Field strength dependence of MRI contrast enhancement: phantom measurements and application to dynamic breast imaging. British Journal of Radiology 69(819): 215-220, 1996

Pulse repetition time and contrast enhancement: simulation study of Gd-BOPTA and conventional contrast agent at different field strengths. Investigative Radiology 43(4): 267-275, 2008

Contrast enhancement in NMR imaging by selection of radiofrequency pulse sequence and time: examples in demyelinating disease. Physiological Chemistry and Physics and Medical Nmr 15(3): 235-237, 1983

The dependence of nuclear magnetic resonance (NMR) image contrast on intrinsic and pulse sequence timing parameters. Magnetic Resonance Imaging 2(1): 3, 1984

Effect of dose and field strength on enhancement with paramagnetic contrast media. Ajnr. American Journal of Neuroradiology 15(10): 1849-1852, 1994

A comparative study on contrast enhancement between 0.5- and 2.0-Tesla field strength in rabbit VX2 carcinomas. Investigative Radiology 30(5): 291-295, 1995

MR characterization of adrenal masses: field strength and pulse sequence considerations. Radiology 171(3): 671-674, 1989

Effect of pulse sequence parameter selection on signal strength in positive-contrast MRI markers for MRI-based prostate postimplant assessment. Medical Physics 43(7): 4312, 2016

Effects of iodinated contrast and field strength on gadolinium enhancement: implications for direct MR arthrography. Journal of Magnetic Resonance Imaging 15(3): 334-343, 2002

Dual mechanisms for change in myocardial signal intensity by means of a single MR contrast medium: dependence on concentration and pulse sequence. Radiology 186(1): 175-182, 1993

Regional corpus callosum morphometry: effect of field strength and pulse sequence. Journal of Magnetic Resonance Imaging 30(5): 1184-1190, 2009

Dynamic Susceptibility Contrast MRI at 7 T: Tail-Scaling Analysis and Inferences About Field Strength Dependence. Tomography 3(2): 74-78, 2017

Aortic 4D flow: quantification of signal-to-noise ratio as a function of field strength and contrast enhancement for 1.5T, 3T, and 7T. Magnetic Resonance in Medicine 73(5): 1864-1871, 2015

Optimal Field Strength and Pulse-Sequence Parameters forin VivoDynamic-Polarization Imaging. Journal of Magnetic Resonance, Series B 113(1): 53-58, 1996