+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

How much ulcer is ulcer-like? Diagnostic determinants of peptic ulcer in open access gastroscopy



How much ulcer is ulcer-like? Diagnostic determinants of peptic ulcer in open access gastroscopy



Family Practice 11(4): 382-388



A cross-sectional diagnostic prevalence study was carried out within a multi-centre experiment with open access gastroscopy in Utrecht, The Netherlands. The objective of the study was to contribute to improvement of patient selection for open access gastroscopy and to evaluate diagnostic determinants for peptic ulcer. Data were analysed in all 861 patients who were consecutively newly referred during the experiment to undergo gastrocopy. Patient characteristics and outcomes of gastroscopies were recorded. Univariate and multivariate (logistic) analyses were carried out and the results were evaluated with ROC (receiver operating characteristic) analysis. The most important clinical characteristics to be used for prediction of peptic ulcer are pain on an empty stomach, absence of pain after a meal and absence of obstructive complaints. The scoring list derived from the full model, comprising these characteristics together with age, sex, information on former dyspeptic diseases, medication and smoking ('basic characteristics'), predicted peptic ulcer with an AUC of 0.78. The 'ulcer-like' model, with characteristics known from the literature, had an AUC of 0.76. The amount of gastroscopy requests on patients suspected of a peptic ulcer could have been reduced from 60 to 44%. Forcing 'basic characteristics' into scoring lists on peptic ulcer improved the pre-diagnostic test capacities. The presented scoring list may improve gastroscopy requesting by GPs aiming at finding peptic ulcers. Practical manageability of the list should be prospectively evaluated in future experiments.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 046280329

Download citation: RISBibTeXText

PMID: 7895965

DOI: 10.1093/fampra/11.4.382


Related references

Vagotomy in the treatment of peptic ulcer near the cardia and of peptic ulcer of jejunum (marginal ulcer, stomal-ulcer). Journal of the Mount Sinai Hospital new York 17(6): 409-422, 1951

Open-access gastroscopy in primary health-care offices to prevent peptic ulcer-related hospitalization and mortality. Scandinavian Journal of Gastroenterology 39(12): 1289-1292, 2004

Open-access gastroscopy in primary health-care offices to prevent peptic ulcer-related hospitalization and mortality. Scandinavian Journal of Gastroenterology 39(12): 1289-1292, 2004

Su1814 Cyp2C19 Genetic Polymorphisms in Patients With Peptic Ulcer Bleeding, Peptic Ulcer Disease and Non-Ulcer Dyspepsia in Thailand. Gastroenterology 144(5): S-480, 2013

Comparative studies on recurrence and relapse rate in peptic ulcer treated with various types of anti-ulcer agent; inhibitors of initiating factors causing peptic ulcer. Nihon Rinsho. Japanese Journal of Clinical Medicine 46(1): 69-78, 1988

Comparative studies on recurrence and relapse rate in peptic ulcer treated with various types of anti-ulcer agent; synergistic drugs for protective factors in peptic ulcer. Nihon Rinsho. Japanese Journal of Clinical Medicine 46(1): 79-83, 1988

Peptic ulcer.Peptic ulcer : Advance on diagnosis and treatment.1.Etiology.3.Helicobacter pylori and peptic ulcer. Nihon Naika Gakkai Zasshi 84(6): 858-863, 1995

Peptic ulcer.Peptic ulcer : Advance on diagnosis and treatment.2.Disease state.3.Infantile peptic ulcer. Nihon Naika Gakkai Zasshi 84(6): 885-889, 1995

Peptic ulcer an international working conference on experimental ulcer held in conjunction with the 4th congress of gastro enterology section on vascular and anatomic considerations in peptic ulcer copenhagen denmark july 13 1970. Pfeiffer, Carl J (Edited By) Peptic Ulcer Symposium Xxiii+356p Illus J B Lippincott Co : Philadelphia, Pa , U S A ; Toronto, Canada 207-263, 1971

Peptic ulcer.Peptic ulcer : Advance in its diagnosis and treatment.2.Morbid state.1.Intractable ulcer. Nihon Naika Gakkai Zasshi 84(6): 873-878, 1995

Peptic ulcer.Peptic ulcer : Advance on diagnosis and treatment.2.Disease state.2.Elderly ulcer. Nihon Naika Gakkai Zasshi 84(6): 879-884, 1995

Peptic ulcer.Peptic ulcer : Advance on diagnosis and treatment.3.Natural history of peptic ulcer. Nihon Naika Gakkai Zasshi 84(6): 890-894, 1995

Peptic ulcer.Peptic ulcer : Advance on diagnosis and treatment.1.Etiology.4.Medicinal ulcer. Nihon Naika Gakkai Zasshi 84(6): 864-867, 1995

Peptic ulcer.Peptic ulcer : Advance on diagnosis and treatment.1.Etiology.5.Stress and ulcer. Nihon Naika Gakkai Zasshi 84(6): 868-872, 1995

Drugs and peptic ulcer: volume 1 - Therapeutic agents for peptic ulcer disease. Volume 2 - Pathogenesis of ulcer induction revealed by studies in humans and animals. Gut 24(9): 869-870, 1983