+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

A metagenomic survey identifies Tamdy orthonairovirus as well as divergent phlebo-, rhabdo-, chu- and flavi-like viruses in Anatolia, Turkey



A metagenomic survey identifies Tamdy orthonairovirus as well as divergent phlebo-, rhabdo-, chu- and flavi-like viruses in Anatolia, Turkey



Ticks and Tick-Borne Diseases 9(5): 1173-1183



We employed a direct metagenomic approach via next-generation sequencing for a cross-sectional investigation of viruses in 10 tick pools, collected from Aegean, Mediterranean and central Anatolian locations in Turkey. Sequences from all genome segments of Tamdy orthonairovirus (family Nairoviridae) were characterized in ticks collected from a Meriones tristrami. We further obtained near-complete L and partial S segments of several tick-associated phleboviruses (family Phenuiviridae), including Tacheng tick virus 2 and a novel virus, tentatively named as the tick phlebovirus Anatolia. Partial NS5-coding region of recently-described flavi-like virus (Tacheng tick virus 8) was further detected. Moreover, near-complete and polymerase-coding regions of arthropod-associated rhabdoviruses as well as sequences closely-related to the members of the newly-proposed virus family, the Chuviridae, were characterized. Despite origins of the viral sequences could not be fully elucidated, the findings suggest the circulation of diverse arthropod and tick-associated viruses in Anatolia. Occurrence and outcome of vertebrate exposure and probable health impact of these viruses require further investigation. We also report the initial detection of Tamdy orthonairovirus, an established human pathogen, which should be included in the diagnostic workup of infections with unknown etiology.

(PDF emailed within 0-6 h: $19.90)

Accession: 046280875

Download citation: RISBibTeXText

PMID: 29728337

DOI: 10.1016/j.ttbdis.2018.04.017


Related references

Complete Genome Coding Sequences of Artashat, Burana, Caspiy, Chim, Geran, Tamdy, and Uzun-Agach Viruses ( Bunyavirales : Nairoviridae : Orthonairovirus ). Genome Announcements 5(40), 2017

A viral metagenomic survey identifies known and novel mammalian viruses in bats from Saudi Arabia. Plos One 14(4): E0214227, 2019

A preliminary survey for viruses and viroids of the Western Anatolia cherry industry in Turkey. Acta Horticulturae: 5(vol 2), 943-945, 2008

Metagenomic analysis of viruses associated with field-grown and retail lettuce identifies human and animal viruses. International Journal of Food Microbiology 223: 50-56, 2016

Cross-species multiplex microarray for serological detection of flavi-, phlebo- and alphaviruses. International Journal of Infectious Diseases 21: 380-381, 2014

A metagenomic viral discovery approach identifies potential zoonotic and novel mammalian viruses in Neoromicia bats within South Africa. Plos One 13(3): E0194527, 2018

Late Triassic-Aptian evolution of the Sakarya divergent margin: Implications for the opening history of the Northern neo-Tethys, in Northwestern Anatolia, Turkey. Geologica Romana 27(0): 81-99, 1991

Frequency of Hepatitis B and C Viruses, and HIV Among Drug Addicts in the Eastern Anatolia, Turkey. Jundishapur Journal of Microbiology 8(8): E19698, 2015

An ethnobotanical survey of Inner-West Anatolia, Turkey. Human Ecology: 5, 763-777, 2008

Research Report: An Ethnobotanical Survey of Inner-West Anatolia, Turkey. Human Ecology 36(5): 763-777, 2008

A radiological survey of the Eğrigöz granitoid, Western Anatolia/Turkey. Radiation Protection Dosimetry 164(4): 510-518, 2016

Occurrence and distribution of stone fruit viruses and viroids in commercial plantings of Prunus species in western Anatolia, Turkey. Journal of Plant Pathology 89(2): 265-268, 2007

A mixed bag. Nursing home chain survey identifies divergent strategies. Contemporary Longterm Care 15(12): 52, 54-7, 1992

Sequence comparison between the phosphoprotein mRNAs of human and bovine respiratory syncytial viruses identifies a divergent domain in the predicted protein. Journal of General Virology 73: 2441-2444, 1992

Human Papilloma Viruses and Their Genotype Distribution in Women with High Socioeconomic Status in Central Anatolia, Turkey: A Pilot Study. Medical Science Monitor 24: 58-66, 2018