+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Identification of a bovine coronavirus packaging signal

Identification of a bovine coronavirus packaging signal

Journal of Virology 74(1): 580-583

A region of the bovine coronavirus (BCV) genome that functions as a packaging signal has been cloned. The 291-nucleotide clone shares 72% homology with the region of mouse hepatitis coronavirus (MHV) gene 1b that contains the packaging signal. RNA transcripts were packaged into both BCV and MHV virions when the cloned region was appended to a noncoronavirus RNA. This is the first identification of a BCV packaging signal. The data demonstrate that the BCV genome contains a sequence that is conserved at both the sequence and functional levels, thus broadening our insight into coronavirus packaging.

Please choose payment method:

(PDF emailed within 1 workday: $29.90)

Accession: 046312804

Download citation: RISBibTeXText

PMID: 10590153

Related references

Identification of a Bovine Coronavirus Packaging Signal. Journal of Virology 74(1): 580-583, 2000

Identification and characterization of a coronavirus packaging signal. Journal of Virology 66(6): 3522-3530, 1992

Identification of a specific interaction between the coronavirus mouse hepatitis virus A59 nucleocapsid protein and packaging signal. Virology 239(1): 78-86, 1997

Cooperation of an RNA packaging signal and a viral envelope protein in coronavirus RNA packaging. Journal of Virology 75(19): 9059-9067, 2001

Murine coronavirus packaging signal confers packaging to nonviral RNA. Journal of Virology 71(1): 824-827, 1997

Genomic relationship of porcine hemagglutinating encephalomyelitis virus to bovine coronavirus and human coronavirus OC43 as studied by the use of bovine coronavirus S gene-specific probes. Archives of virology40(7): 1215-1223, 1995

Identification of a coronavirus hemagglutinin-esterase with a substrate specificity different from those of influenza C virus and bovine coronavirus. Journal of Virology 73(5): 3737-3743, 1999

Functional analysis of the murine coronavirus genomic RNA packaging signal. Journal of Virology 87(9): 5182-5192, 2013

Transmissible gastroenteritis coronavirus packaging signal is located at the 5' end of the virus genome. Journal of Virology 77(14): 7890-7902, 2003

Analysis of efficiently packaged defective interfering RNAs of murine coronavirus: localization of a possible RNA-packaging signal. Journal of Virology 64(12): 6045-6053, 1990

Recognition of the murine coronavirus genomic RNA packaging signal depends on the second RNA-binding domain of the nucleocapsid protein. Journal of Virology 88(8): 4451-4465, 2014

Nucleocapsid protein-dependent assembly of the RNA packaging signal of Middle East respiratory syndrome coronavirus. Journal of Biomedical Science 25(1): 47, 2018

Assembly of severe acute respiratory syndrome coronavirus RNA packaging signal into virus-like particles is nucleocapsid dependent. Journal of Virology 79(22): 13848-13855, 2005

The primary nucleotide sequence of the bovine leukemia virus RNA packaging signal can influence efficient RNA packaging and virus replication. Virology 301(2): 272-280, 2002

A subgenomic mRNA transcript of the coronavirus mouse hepatitis virus strain A59 defective interfering (DI) RNA is packaged when it contains the DI packaging signal. Journal of Virology 71(7): 5684-5687, 1997