+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Identification of a novel substrate of Alzheimer's beta-secretase: beta-secretase dependent cleavage of alpha 2,6 sialyltransferase



Identification of a novel substrate of Alzheimer's beta-secretase: beta-secretase dependent cleavage of alpha 2,6 sialyltransferase



Seikagaku. Journal of Japanese Biochemical Society 74(9): 1180-1183




Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 046313672

Download citation: RISBibTeXText

PMID: 12402461


Related references

Characterization of alpha 2,6-sialyltransferase cleavage by Alzheimer's beta -secretase (BACE1). Journal of Biological Chemistry 278(17): 14865-14871, 2002

Protein kinase C-dependent alpha-secretase competes with beta-secretase for cleavage of amyloid-beta precursor protein in the trans-golgi network. Journal of Biological Chemistry 275(4): 2568-2575, 2000

In vivo cleavage of alpha2,6-sialyltransferase by Alzheimer beta-secretase. Journal of Biological Chemistry 280(9): 8589-8595, 2004

Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase. Proceedings of the National Academy of Sciences of the United States of America 98(24): 13554-9, 2001

Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity. Journal of Biological Chemistry 278(23): 21286-21294, 2003

Competition for APP cleavage by regulated alpha-secretase and beta-secretase. Society for Neuroscience Abstracts 25(1-2): 595, 1999

Levels of beta-secretase BACE and alpha-secretase ADAM10 mRNAs in Alzheimer hippocampus. Neuroreport 13(16): 2031-2033, 2002

Purification and characterization of forms of s-beta-PP specifically cleaved at alpha-secretase or beta-secretase sites. Neurobiology of Aging 15(SUPPL 1): S634-S64, 1994

Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain. Journal of Neurochemistry 75(5): 2133-2143, 2000

Involvement of proteases in glycosyltransferase secretion: Alzheimer's beta-secretase-dependent cleavage and a following processing by an aminopeptidase. Glycoconjugate Journal 21(1-2): 25-29, 2004

Novel alpha-secretase cleavage of Alzheimer's amyloid beta precursor protein in the endoplasmic reticulum of COS7 cells. Neuroscience Letters 376(1): 14-19, 2005

Short-term interleukin-1(beta) increases the release of secreted APP(alpha) via MEK1/2-dependent and JNK-dependent alpha-secretase cleavage in neuroglioma U251 cells. Journal of Neuroscience Research 80(5): 683-692, 2005

Thioredoxin-80 is a product of alpha-secretase cleavage that inhibits amyloid-beta aggregation and is decreased in Alzheimer's disease brain. Embo Molecular Medicine 4(10): 1097-1111, 2013

In Vivo Cleavage of 2,6-Sialyltransferase by Alzheimer -Secretase. Journal of biological chemistry4 280(9): 8589-8595, 2005

Evidence that gamma-secretase mediates oxidative stress-induced beta-secretase expression in Alzheimer's disease. Neurobiology of Aging 31(6): 0-925, 2010