+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Internal dosimetry for inhalation of hafnium tritide aerosols



Internal dosimetry for inhalation of hafnium tritide aerosols



Radiation Protection Dosimetry 93(1): 55-60



Metal tritides with low dissolution rates may have residence times in the lungs which are considerably longer than the biological half-time normally associated with tritium in body water, resulting in long-term irradiation of the lungs by low energy beta particles and bremsstrahlung X rays. Samples of hafnium tritide were placed in a lung simulant fluid to determine approximate lung dissolution rates. Hafnium hydride samples were analysed for particle size distribution with a scanning electron microscope. Lung simulant data indicated a biological dissolution half-time for hafnium tritide on the order of 10(5) d. Hafnium hydride particle sizes ranged between 2 and 10 microns, corresponding to activity median aerodynamic diameters of 5 to 25 microns. Review of in vitro dissolution data, development of a biokinetic model, and determination of secondary limits for 1 micron AMAD particles are presented and discussed.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 046439273

Download citation: RISBibTeXText

PMID: 11548328

DOI: 10.1093/oxfordjournals.rpd.a006413


Related references

Determination of the hydrolysis rate of hafnium tritide. La Reports . U.S. Atomic Energy Commission Lams-2526: 302-305, 1961

Dose estimate of inhaled hafnium tritide using the ICRP 66 lung model. Health Physics 82(6): 817-824, 2002

Repeated Inhalation Exposure of Rats to Aerosols of${}^{144}{ rm CeO}{}_{2}$: I. Lung, Liver, and Skeletal Dosimetry. Radiation Research 132(3): 312-324, 1992

Repeated inhalation exposure of rats to aerosols of 144CeO2. I. Lung, liver, and skeletal dosimetry. Radiation Research 132(3): 312-324, 1992

Influence of age at the time of inhalation exposure to aerosols of 144CeO2 on 144Ce retention, dosimetry and toxicity in mice. Health Physics 38(4): 643-655, 1980

Inhalation toxicology of industrial plutonium and uranium oxide aerosols part 2 deposition retention and dosimetry. Health Physics 35(6): 888, 1978

Internal dosimetry of nuclear medicine workers through the analysis of (131)I in aerosols. Applied Radiation and Isotopes 100: 70-74, 2015

Biokinetics and dosimetry of titanium tritide particles in the lung. Health Physics 76(2): 120-128, 1999

Spectral emissions and dosimetry of metal tritide particulates. Radiation Protection Dosimetry 98(4): 389-400, 2002

Biokenetics and Dosimetry of Titanium Tritide Particles in the Lung. Health Physics 76(2): 120-128, 1999

Metabolic kinetics and dosimetry of titanium tritide particles in the lung. Health Physics 70(6 Suppl. ): S82-S83, 1996

Particle size-dependent total mass deposition in lungs determines inhalation toxicity of cadmium chloride aerosols in rats. Application of a multiple path dosimetry model. Archives of Toxicology 76(5-6): 277-286, 2002

Influence of age at the time of inhalation exposure to aerosols of cerium 144 labeled cerium di oxide on cerium 144 retention dosimetry and toxicity in mice. Health Physics 38(4): 643-656, 1980

A novel aerosol inhalation device for pressurized metered dose inhalation aerosols: Gammascintigraphic evaluation of pulmonary deposition profiles and comparison with commercial inhalation devices. International Journal of Pharmaceutics 128(1-2): 55-63, 1996

A novel aerosol inhalation device for pressurized metered dose inhalation aerosols: Gamma scintigraphic evaluation of pulmonary deposition profiles and comparison with commercial inhalation devices. International Journal of Pharmaceutics (Amsterdam) 128(1-2): 55-63, 1996