+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Local recurrence following total mesorectal excision for rectal cancer



Local recurrence following total mesorectal excision for rectal cancer



British Journal of Surgery 83(3): 375-379



Early results after rectal cancer surgery in a defined population were compared before and after the introduction of total mesorectal excision. In the first period (1984-1986) 211 cases of rectal cancer were diagnosed and in the second (1990-1992) 230. Of these, 134 patients in the first period (group 1) had anterior resection or abdominoperineal excision which was considered curative. In the second period 128 curative anterior resections and abdominoperineal excisions were performed by a limited number of surgeons familiar with total mesorectal excision (group 2). No differences between the groups were found in stage distribution, rate of curative operations, postoperative complications or postoperative mortality. Local recurrence had developed in 19 patients in group 1 and in eight in group 2, 1 year after the end of the study periods (P = 0.03). Local radicality was in doubt in 13 patients in group 1 and in eight in group 2. In the remaining 121 and 120 patients, 13 and four local recurrences respectively were present (P = 0.03). Actuarial analysis showed a significant reduction in local recurrence rate (P = 0.03) and an increase in crude survival (P = 0.03) at 4 years in group 2 compared with group 1. Total mesorectal excision reduces the local recurrence rate after excision of rectal cancer.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 046561193

Download citation: RISBibTeXText

PMID: 8665198

DOI: 10.1002/bjs.1800830326


Related references

Local recurrence of rectal cancer following total mesorectal excision with or without preoperative radiotherapy. European Surgical Research 32(Suppl 1): 12, 2000

Local recurrence of rectal cancer after total mesorectal excision without preoperative radiotherapy. International Journal of Gastrointestinal Cancer 34(2-3): 129-134, 2004

Comparison of local recurrence of rectal cancer after two radical operations using total mesorectal excision. Zhonghua Wai Ke Za Zhi 40(11): 820-825, 2002

Factors associated with local recurrence after neoadjuvant chemoradiation with total mesorectal excision for rectal cancer. World Journal of Surgery 33(8): 1741-1749, 2009

Effect of total mesorectal excision and preoperative chemoradiotherapy on local recurrence in rectal cancer. Zhonghua Wei Chang Wai Ke Za Zhi 9(3): 207-209, 2006

Local recurrence in patients treated for rectal cancer using total mesorectal excision or transection of mesorectum. Vojnosanitetski Pregled 73(10): 927-933, 2018

Total Mesorectal Excision Results in Low Local Recurrence Rates in Lymph Node-Positive Rectal Cancer. Diseases of the Colon & Rectum -1(1): 1, 2004

Total mesorectal excision and local recurrence: a study of tumour spread in the mesorectum distal to rectal cancer. British Journal of Surgery 82(8): 1031-1033, 1995

Total mesorectal excision results in low local recurrence rates in lymph node-positive rectal cancer. Diseases of the Colon and Rectum 47(7): 1145-9; Discussion 1149-50, 2004

Tumor stroma: a determinant role in local recurrence of rectal cancer patients receiving total mesorectal excision?. Medical Hypotheses 75(5): 442-444, 2011

Local cancer recurrence after standard rectal resection and rectal resection with total mesorectal excision. Digestive Surgery 15(5): 629, 1998

The impact of the introduction of total mesorectal excision on local recurrence rate and survival in rectal cancer: long-term results. Annals of Surgical Oncology 18(7): 1899-1906, 2011

The influence of total mesorectal excision on local recurrence and survival in rectal cancer patients: a population-based study in Greater Amsterdam. Journal of Surgical Oncology 95(6): 447-454, 2006

Investigation on complementarity between total mesorectal excision and radical resection in relation to postoperative local recurrence in patients receiving anus-reserve operation on rectal cancer. Chinese-German Journal of Clinical Oncology 6(4): 325-327, 2007

Local recurrence after mesorectal excision for rectal cancer. European Journal of Surgical Oncology 28(2): 126-134, 2002