Long partial response (PR) in a case of multiple liver metastasis from colon cancer effectively treated by continuous hepatic intra-arterial infusion chemotherapy
Wakahara, M.; Tanaka, S.; Tanemura, H.; Ooshita, H.; Kanno, A.; Hiraoka, T.; Suhara, T.; Nakata, T.; Yamamoto, M.; Saitou, S.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 26(12): 1917-1920
ISSN/ISBN: 0385-0684 PMID: 10560425 Accession: 046566036
The patient was a 69-year-old man who had undergone a sigmoidectomy for cancer of the sigmoid colon on March 25, 1993. We detected the elevation of CEA after the operation. Computed tomography revealed multiple metastasis of the liver on September 3, 1996. After beginning 48-hour continuous hepatic arterial infusion using 5-FU 1,000 mg and Leucovorin 30 mg, we recognized a decrement of metastatic liver tumor. We could not detect cancer cells by needle biopsy for liver tumors on February 19, 1998. This case is maintaining good quality of life by hepatic artery infusion using 5-FU and Leucovorin, showing a long PR for about two years. We think that this case shows ideal clinical progress from chemotherapy for cancer of the digestive organs.