+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Long-range intermolecular interaction between broken DNA fragments



Long-range intermolecular interaction between broken DNA fragments



Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics 63(3 Pt 1): 031904



We analyzed the long-range intermolecular interaction between fragments of broken DNA. We considered two constituents of long-range intermolecular interaction. The first is a net electrostatic Coulomb interaction between charges, involved in a structure of opposite nucleotides, which we evaluate using Debye-Huckel theory. The second one is the Van der Waals interaction between the nucleotides. The general Lifshitz theory of Van der Waals forces was used to evaluate this interaction. Numerical calculations showed that a repulsive force between broken DNA fragments can arise in specific cases. This repulsion can prevent DNA from repairing itself after a double-strand break. The height of the barrier decreases with an increase of the ionic strength of the intracellular milieu, or with a reduction of its viscosity.

(PDF emailed within 0-6 h: $19.90)

Accession: 046567143

Download citation: RISBibTeXText

PMID: 11308675

DOI: 10.1103/PhysRevE.63.031904


Related references

Peculiarities of long-range interaction between broken DNA fragments. Biophysical Journal 78(1 Part 2): 170A, 2000

Interaction of red blood cells with a polarized electrode: evidence of long-range intermolecular forces. Biophysical Journal 16(10): 1131-1153, 1976

Generalized Intermolecular Interaction Tensor Applied to Long-Range Interactions in Hydrogen and Coinage Metal (Cu, Ag, and Au) Clusters. Journal of Physical Chemistry. a 119(48): 11729-11736, 2015

Long-range intermolecular charge transfer induced by laser pulses: an explicitly time-dependent configuration interaction approach. Physical Chemistry Chemical Physics 11(20): 3875-3884, 2009

From short-range to long-range intermolecular NOEs in ionic liquids: frequency does matter. Angewandte Chemie 52(35): 9242-9246, 2014

The influence of aromatic fragments on the intermolecular interaction of phosphoryl compounds with the medium. Russian Chemical Bulletin 23(9): 1952-1955, 1974

Biophysical study of molecular mechanism of abortificient action of prostaglandins. II. The study of the long and short range interaction between different fragments of PGF2 alpha, PGF1 beta and PGA1. Journal of Theoretical Biology 93(1): 25-40, 1981

The long range model of intermolecular forces. Molecular Physics 50(6): 1349-1361, 1983

Long and short range intermolecular and intercolloidal forces. Current Opinion in Colloid & Interface Science 1(1): 53-60, 1996

Long range intermolecular interactions between the alkali diatomics Na(2), K(2), and NaK. Journal of Chemical Physics 132(24): 244305, 2010

Experimental observation of soliton interaction over long fiber paths: discovery of a long-range interaction. Optics Letters 14(22): 1284-1286, 1989

The role of long-range intermolecular interactions in discovery of new drugs. Expert Opinion on Drug Discovery 6(12): 1263-1270, 2012

Chemical reactions dominated by long-range intermolecular forces. Faraday Discussions of the Chemical Society 84(0): 333-0, 1987

Long-range dispersal, stochasticity and the broken accelerating wave of advance. Theoretical Population Biology 100c: 39-55, 2014

Rates of chemical reactions dominated by long-range intermolecular forces. Molecular Physics 53(1): 3-21, 1984