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Long-term ambulatory follow-up of hypertension patients with low renin activity in blood

Long-term ambulatory follow-up of hypertension patients with low renin activity in blood

Terapevticheskii Arkhiv 74(9): 57-59

To characterize a clinical course of arterial hypertension in patients with low activity of blood renin. 44 hypertensive patients with low activity of blood renin participated in the trial. They were divided into three groups consisting of 18, 14 and 12 patients (group 1, 2 and 3 with adrenal adenoma, adrenal hyperplasia and hypertension, respectively). Baseline hypertension was higher in group 1. The clinical picture did not differ much between the groups. Long-term follow-up has revealed that mean arterial pressure tended to lowering in groups 1 and 2 while in group 3 it tended to rise. Incidence of arrhythmia increased thrice though myasthenia became less frequent. Group 1 patients had a more severe clinical course of hypertension with high lethality and many associated diseases. To achieve a clinical effect, they had to take higher doses of antihypertensive drugs.

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Accession: 046567462

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PMID: 12418122

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