Molecular characterization of a gene locus encoding biosynthesis pathway of Streptococcus mutans serotype C-specific antigen

Yamashita, Y.; Tsukioka, Y.; Oho, T.; Nakano, Y.; Koga, T.

Advances in Experimental Medicine and Biology 418: 1011-1014


ISSN/ISBN: 0065-2598
PMID: 9331822
Accession: 046710540

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Almost all streptococci possess rhamnose in their cell-wall polysaccharides as a characteristic constituent. Many streptococcal cell-wall polysaccharides have been chemically characterized and it was found that serotype-specific polysaccharide antigens of Streptococcus mutans are composed of polyrhamnose backbone structure identical to those of the rhamnose-glucose polysaccharide antigen of Streptococcus sobrinus and the group-specific polysaccharide antigens of Lancefield group A, C and E streptococci. S. mutans strains are classified into three serotypes, c, e, and f, based on the serological properties of the cell-wall polysaccharides and the serotype specificity of S. mutans is determined by the linkage of glucose residues as side chains4,.