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Nonimmunological factors affecting the release of excreted/secreted antigens from Toxoplasma gondii cysts



Nonimmunological factors affecting the release of excreted/secreted antigens from Toxoplasma gondii cysts



Zentralblatt für Bakteriologie 284(2-3): 378-389



The phenomenon of released Toxoplasma gondii cyst antigens was studied immunohistochemically and cytochemically. It could be demonstrated that the preservation and localization of excreted/secreted antigens depended not only on the technique of preparation and fixation of the infected tissue but also on the preservation of the host cell. The soluble, bradyzoite-secreted amorphous cyst matrix material is released either after host cell destruction or permeabilization of the cyst wall. Ultrastructural studies could prove that the liberation of the cyst from its host cell does not affect the basic structure of the cyst wall but causes stretching of the invaginated limiting membrane.

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Accession: 046816312

Download citation: RISBibTeXText

PMID: 8837399

DOI: 10.1016/s0934-8840(96)80114-9


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