+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Optic disc elevation in Down syndrome



Optic disc elevation in Down syndrome



Ophthalmic Genetics 20(1): 45-51



Optic disc elevation associated with Down syndrome is an uncommon phenomenon and raises the suspicion of an intracranial space-occupying lesion, thus necessitating the consideration of invasive and noninvasive investigations. Four patients with Down syndrome and optic disc elevation without an underlying intracranial pathology are reported. Thorough ophthalmological and neuroradiological investigations were performed on each patient. Mild hyperopia occurred in three patients and myopia in one. We believe that in most Down syndrome patients with disc elevation, fluorescein angiography and/or clinical follow-up may be sufficient.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 046870647

Download citation: RISBibTeXText

PMID: 10415465

DOI: 10.1076/opge.20.1.45.2297


Related references

Appearance of optic disc drusen in a patient with anomalous elevation of the optic disc. Archives of Ophthalmology 104(6): 794-795, 1986

Membrane tissue on the optic disc may cause macular schisis associated with a glaucomatous optic disc without optic disc pits. Clinical Ophthalmology 7: 883-887, 2013

A patient with anomalous optic disc elevation. JournalofNeuro-Ophthalmology20(4):294, 2000

Retinal nerve fiber analysis and tomography of the optic disc in eyes with tilted disc syndrome. Ophthalmic Surgery Lasers and Imaging 36(6): 494-502, 2005

Congenital optic disc anomalies simulating morning glory syndrome without excavation of disc area. Rinsho Ganka 43(9): 1377-1384, 1989

Peroxidase diffusion in the optic disc following acute elevation of intraocular pressure. Nippon Ganka Gakkai Zasshi 91(5): 589-598, 1987

Anomalous optic disc elevation associated with ultrasonographic evidence of increased subarachnoid fluid. Journal of Neuro-Ophthalmology 20(1): 25-27, 2000

Optic disc evaluation in optic neuropathies: the optic disc assessment project. Ophthalmology 118(5): 964-970, 2011

Visual prognosis of optic nerve sheath meningiomas producing shunt vessels on the optic disc the hoyt spencer syndrome. Kearns, Thomas P (Ed ) Transactions Of The American Ophthalmological Society, Vol 75 113th Annual Meeting Hot Springs, Va , Usa, May 30, 1977 Xxiv+679p Illus Whiting Press, Inc : Rochester, Minn , Usa 141-163, 1978

Analysis of retinal function in the morning glory syndrome and similar anomalies of the optic disc: II. Optic nerve papilla dysplasia. Pathogenesis of lesions. Klinika Oczna 83(4-5): 261-262, 1981

Identification of optic disc elevation and the crescent sign using point-of-care ocular ultrasound in children. Pediatric Emergency Care 31(4): 304-307, 2015

Rates of change in the visual field and optic disc in patients with distinct patterns of glaucomatous optic disc damage. Ophthalmology 119(2): 294-303, 2012

Evaluation of optic disc drusen, pseudotumor cerebri and inflammatory diseases of the optic disc by optical coherence tomography. Investigative Ophthalmology & Visual Science 36(4): S454, 1995

Optic disc and peripapillary retinal nerve fiber layer characteristics associated with glaucomatous optic disc in young myopia. Graefe's Archive for Clinical and Experimental Ophthalmology 255(3): 591-598, 2017

The influence of age, gender, refractive error, and optic disc size on the optic disc configuration in Japanese normal eyes. Acta Ophthalmologica Scandinavica 78(2): 200-203, 2000