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Optic disc swelling in Crohn's disease



Optic disc swelling in Crohn's disease



Australian and New Zealand Journal of Ophthalmology 26(4): 329-332



To provide a review of the causes of optic disc swelling in patients suffering from inflammatory bowel disease. Two illustrative cases of bilateral optic disc swelling are presented: one in a patient known to have Crohn's disease and the other in a patient whose investigations revealed the disease. The possible causes of optic disc swelling in inflammatory bowel disease, based on a literature review, are tabulated and discussed with reference to the presented cases. Optic disc swelling is a rare complication of inflammatory bowel disease. Previously reported cases have been attributed to peripapillary inflammation, optic disc ischaemia or intracranial hypertension. Postulated causes of optic nerve ischaemia include a local vasculitis or general hypercoagulability. The underlying aetiology of intracranial hypertension is often elusive. Older studies suggest a relationship between corticosteroid treatment and/or iron deficiency anaemia, while modern imaging emphasises the need to exclude dural venous sinus thrombosis.

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Accession: 046870675

Download citation: RISBibTeXText

PMID: 9843262

DOI: 10.1111/j.1442-9071.1998.tb01338.x


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