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Optic nerve involvement in acute lymphoblastic leukemia

Optic nerve involvement in acute lymphoblastic leukemia

Leukemia and Lymphoma 11(1-2): 153-155

Leukemic infiltration of the optic nerve is rare. We describe the diagnostic assessment and the outcome in two adult patients suffering from acute lymphoblastic leukemia with T phenotype. In both cases the leukemic involvement of the eye was observed as an isolated extramedullary relapse followed after several months by hematological relapse. CT and MRI scans were negative, while an A-scan echography of the eye clarified the diagnosis. Early radiotherapy caused recovery of visual acuity in one case. A-scan echography is the most sensitive investigation for the early recognition of ocular localization in acute leukemias.

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Accession: 046870798

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PMID: 8220151

DOI: 10.3109/10428199309054745

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