+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Optic neuropathy in uremia: an interdisciplinary emergency



Optic neuropathy in uremia: an interdisciplinary emergency



American Journal of Kidney Diseases 37(3): E23



Optic neuropathy in uremia is rare. Although the consequences of optic neuropathy-blindness or substantial loss of vision-are devastating, only a few cases have been reported by way of single case reports and case series studies. The reported patients are heterogeneous with regard to the cause of neuropathy. We report the case of a patient with uremic optic neuropathy and summarize the other cases reported in the literature so far. Based on the data available from these reports, we propose a classification system, which includes nonischemic neurotoxic uremic optic neuropathy; ischemic optic neuropathy, more specifically anterior ischemic optic neuropathy; and optic neuropathy as a result of drug side effects, benign intracranial hypertension, and optic neuritis. The immediate institution of dialysis and corticosteroid therapy and correction of anemia and relative hypotension can optimize the chances of visual recovery for these patients. Close collaboration among nephrologists, ophthalmologists, and neurologists is important in this interdisciplinary emergency.

(PDF emailed within 0-6 h: $19.90)

Accession: 046870901

Download citation: RISBibTeXText

PMID: 11228200

DOI: 10.1053/ajkd.2001.22101


Related references

Optic neuropathy in uremia. American Journal of Ophthalmology 108(1): 30-35, 1989

Comparison of optic disc morphology of optic nerve atrophy between compressive optic neuropathy and glaucomatous optic neuropathy. Plos One 9(11): E112403, 2015

Comparative studies of the pattern visually evoked potentials in traumatic optic neuropathy, optic neuritis and ischemic optic neuropathy. IOVS 42(4): S788, March 15, 2001

Vep pattern differentiation of anterior ischemic optic neuropathy aion demyelinative optic neuritis and compressive optic neuropathy. Neurology 40(4 SUPPL 1): 312, 1990

Quantitative comparison of disc rim color in optic nerve atrophy of compressive optic neuropathy and glaucomatous optic neuropathy. Graefe's Archive for Clinical and Experimental Ophthalmology 254(8): 1609-1616, 2017

Multifocal visual evoked potential in optic neuritis, ischemic optic neuropathy and compressive optic neuropathy. Indian Journal of Ophthalmology 62(3): 299-304, 2015

Traumatic optic neuropathy should be managed as an ophthalmic emergency. Chinese Journal of Ophthalmology 44(8): 673-675, 2010

51-year-old female with steroid-responsive optic neuropathy: a new case of chronic relapsing inflammatory optic neuropathy (CRION). Journal of Neurology 255(9): 1419-1420, 2008

Confirmation that neither cyanide intoxication nor mutations commonly associated with Leber's Hereditary Optic Neuropathy are implicated in Tanzanian Epidemic Optic Neuropathy. Journal of the Neurological Sciences 152(1): 107-108, 1997

Effect of transcorneal electrical stimulation in patients with nonarteritic ischemic optic neuropathy or traumatic optic neuropathy. Japanese Journal of Ophthalmology 50(3): 266-273, 2006

Prevalence of mtDNA mutations associated with Lebers hereditary optic neuropathy in familial MS and MS patients with prominent optic neuropathy. Neurology 50(4 SUPPL 4): A149, April, 1998

Alcohol and smoking induced optic neuropathy versus Leber's hereditary optic neuropathy: A pitfall diagnostic. Revue Neurologique (Paris) 150(11): 799-801, 1994

Two secondary Lebers hereditary optic neuropathy mutations found in a family with maternal inherited multisystem disorder lacking optic neuropathy. Modern Pathology 17(2): 270, February, 2004