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Phenotypic and functional characterization of mouse hepatic CD8 alpha+ lymphoid-related dendritic cells



Phenotypic and functional characterization of mouse hepatic CD8 alpha+ lymphoid-related dendritic cells



Journal of Immunology 165(2): 795-803



Recently, attention has focussed on phenotypic and functional differences between classic myeloid dendritic cells (DC), and DC that reportedly develop from an early, committed lymphoid precursor. In mice, DC from these separate hemopoietic lineages differ by their surface expression of CD8 alpha. We undertook a comparative study of CD8 alpha+ (CD11blow; lymphoid-related) and CD8 alpha- (CD11bhigh; myeloid) DC isolated from mouse liver. CD8 alpha+ and CD8 alpha- DC each constituted

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Accession: 046973848

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PMID: 10878353


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