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An end in sight? Xrn2 and transcriptional termination by RNA polymerase II



An end in sight? Xrn2 and transcriptional termination by RNA polymerase II



Transcription 9(5): 321-326



Every transcription cycle ends in termination when RNA polymerase dissociates from the DNA. Although conceptually simple, the mechanism has proven somewhat elusive in eukaryotic systems. Gene-editing and high resolution polymerase mapping now offer clarification of important steps preceding transcriptional termination by RNA polymerase II in human cells.

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Accession: 047164882

Download citation: RISBibTeXText

PMID: 30035655

DOI: 10.1080/21541264.2018.1498708


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