+ Site Statistics
+ Resolve Accession
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
Submit PDF Full TextSubmit PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

Removal of basiliximab by plasmapheresis

, : Removal of basiliximab by plasmapheresis. American Journal of Kidney Diseases 37(1): E11-E11

Basiliximab is a chimeric monoclonal antibody directed against the alpha chain of interleukin-2 (IL-2) receptors. Given its expected volume of distribution (plasma volume), therapeutic plasmapheresis may be expected to lower serum Basiliximab levels. A 20-mg dose of Basiliximab was given before plasmapheresis. Blood and pheresis fluid samples were obtained to monitor Basiliximab levels. A total of three blood samples were drawn: the first was obtained 4 hours before, the second sample immediately before commencement, and the third 2 hours after cessation of plasmapheresis. A fourth sample was obtained from the removed plasma. There was an appreciable reduction in Basiliximab concentration levels after plasmapheresis. From the change in serum concentration after plasmapheresis, approximately 64.6% of circulating Basiliximab was removed. Plasmapheresis removes substantial amounts of Basiliximab. Therefore, supplemental Basiliximab should be given after plasmapheresis to maintain the desired duration of IL-2R saturation.

(PDF 0-2 workdays service)

Order PDF Full Text


Click here to order any other PDF Full Text

Accession: 047230853

PMID: 11136200

PDF Full Text: Submit

Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:

Other references

Pedersen, H; Cho, Gh; Kim, D; Cazzulino, D; Chin, Ck, 1988: Mass transfer in plant cell systems. Proceedings: 8th International Biotechnology Symposium Paris 1988 edited by G Durand L Bobichon J Florent: 488

Raviv O.; Heller H.; Hershko A., 1987: Alterations in components of the ubiquitin protein ligase system following maturation of reticulocytes to erythrocytes. Previous studies have shown that the activity of the ubiquitin-mediated proteolytic system declines markedly following reticulocyte maturation, but the specific alterations responsible for this phenomenon have not been defined. We find that the ra...

Schipper M.A.A., 1979: Thermomucor mucorales. T. indicae-seudaticae is described in the order Mucorales. Descriptions and illustrations of both the zygosporic and sporangial states are presented.

Nicholas P.J.; Mcginnies W.J., 1982: An evaluation of 17 grasses and 2 legumes for re vegetation of soil and spoil on a coal strip mine. Seventeen grass species [Festuca arizonica, F. ovina duriuscula, F. arundinacea, Phleum pratense, Dactylis glomerata, Bromus marginatus, B. inermis, Agropyron trachycaulon, A. intermedium, A. intermedium var. trichophorum, A. smithii, A. dasystach...

Platt, N. E., 1975: Infestation of cod (Gadus morhua L.) with larvae of codworm (Terranova decipiens Krabbe) and herringworm, Anisakis sp. (Nematoda, Ascaridata), in North Atlantic and Arctic waters. Nearly 5,300 Gadus morhua collected from the North Atlantic and Arctic during 1971-73 were examined for larvae of Terranova decipiens and Anisakis sp. The nematode burdens showed strong positive correlations with fish size and age. T. decipiens wa...

Picaud, S.; Becq, F.; Dedaldechamp, F.; Ageorges, A.; Delrot, S., 2003: Cloning and expression of two plasma membrane aquaporins expressed during the ripening of grape berry. The ripening of grape (Vitis vinifera) berry is accompanied by dramatic accumulation of sugars and water. Two full-length clones and several partial clones encoding plasma membrane aquaporins (PIP) were cloned from grape berries collected at the b...

Kusumoto, Fred, M.; Muhiudeen, Isobel, A.; Kuecherer, Helmut, F.; Cahalan, Michael, K.; Schiller, Nelson, B., 1993: Response of the interatrial septum to transatrial pressure gradients and its potential for predicting pulmonary capillary wedge pressure: An intraoperative study using transesophageal echocardiography in patients during mechanical ventilation. Objectives: We hypothesized that the directional movement of the interatrial septum and its curvature may reflect the pressure relations between the left and right atria. Background: Interventricular septal shape is primarily dependent on the pres...

Zhang, X.G., 1989: Sternal turnover with preservation of internal mammary vessels in the treatment of pectus excavatum. This article reports the experience of using a modified sternal turnover technique in 4 patients with pectus excavatum in which one or both internal mammary vascular pedicles were preserved to assure viability of the sternum and costal cartilages...

Sanchez Botija, R., 1951: Mycotic infection of the abomasum in anox. The author described ulceration of the abomasum in an ox caused by a fungus of the Mucor class. He described the microscopic characters of the lesion.

Hopp, H. P.; Geisler, S.; Zahm, D. S.; Veh, R. W., 2001: Diencephalic and telencephalic connections of subdivisions of the lateral habenula. Distributions in afferent and efferent connections of the lateral habenula (LHb) were investigated by means of iontopheretic injection of anterograde tracers (PHA-L, Fluoro-ruby) into the LHb. The exact localization of all labeled areas in the LHb...